Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.61 |
| ▸ | CES1 | P23141 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30954392 | 0.85 | CES2 (0.68) | CES2CES1RAB9AMAPTL3MBTL1 | |
| SCHEMBL8359445 | 0.83 | CES2 (0.65) | CES2CES1RAB9AMAPTL3MBTL1 | |
| SCHEMBL5651048 | 0.83 | CES2 (0.65) | CES2CES1RAB9AMAPTL3MBTL1 | |
| SCHEMBL523258 | 0.80 | CES2 (0.61) | CES2CES1RAB9AMAPTL3MBTL1 | |
| SCHEMBL14012584 | 0.80 | CES2 (0.61) | CES2CES1RAB9AMAPTL3MBTL1 | |
| SCHEMBL24779498 | 0.80 | CES2 (0.61) | CES2CES1RAB9AMAPTL3MBTL1 | |
| SCHEMBL20551726 | 0.80 | CES2 (0.61) | CES2CES1RAB9AMAPTL3MBTL1 | |
| SCHEMBL6968044 | 0.80 | CES2 (0.61) | CES2CES1RAB9AMAPTL3MBTL1 | |
| SCHEMBL2831243 | 0.77 | CES2 (0.57) | CES2CES1RAB9AMAPTALDH1A1 | |
| SCHEMBL23421455 | 0.77 | CES2 (0.57) | CES2CES1RAB9AMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107835805-A | Substituted benzamides and methods of use thereof | 基因泰克公司 | 2018-03-23 | — | — | CN | disclosed |
| CN-106278860-A | A kind of synthetic method of 3 chlorine 2,4 difluoro-benzoic acids | 常州工程职业技术学院 | 2017-01-04 | — | — | CN | disclosed |
| CN-106278860-A | A kind of synthetic method of 3 chlorine 2,4 difluoro-benzoic acids | 常州工程职业技术学院 | 2017-01-04 | — | — | CN | disclosed |
| CN-102887891-B | N4-phenyl-quinazoline-4-sulfonamide derivatives and related compound | ARRAY BIOPHARMA INC. (US) | 2016-03-09 | — | — | CN | disclosed |
| CN-104718188-A | N-substituted benzamides and their use in the treatment of pain | GENENTECH INC | 2015-06-17 | — | — | CN | disclosed |