SCHEMBL28018902

SCHEMBL28018902

[SiH4].c1ccc(-c2oc(-c3ccccc3)c3ccccc23)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.44
CA12 O43570 2/20 0.44
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
TP53 P04637 2/20 0.44
ABCB1 P08183 2/20 0.44
CYP3A4 P08684 2/20 0.44
AR P10275 2/20 0.44
CYP1B1 Q16678 2/20 0.44
CA9 Q16790 2/20 0.44
ADORA3 P0DMS8 2/20 0.44
ALOX15 P16050 2/20 0.44
MEN1 O00255 2/20 0.44
LMNA P02545 2/20 0.44
KMT2A Q03164 2/20 0.44
DDR2 Q16832 1/20 0.44
CALM1 P0DP23 1/20 0.44
PKM P14618 1/20 0.44
MAPK1 P28482 1/20 0.44
ALDH1A1 P00352 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27936018 0.97 KDM4E (0.45) KDM4ECA12CA1CA2TP53
SCHEMBL297968 0.97 KDM4E (0.45) KDM4ECA12CA1CA2TP53
SCHEMBL23596264 0.92 ALDH1A1 (0.47) KDM4ECA12CA1CA2TP53
Dimethyl Sulfoxide SCHEMBL28943703 0.84 ABCG2 (0.40) KDM4ECA12CA1CA2TP53
Alcohol SCHEMBL28338495 0.84 KDM4E (0.42) KDM4ECA12CA1CA2TP53
SCHEMBL3681192 0.84 ALDH1A1 (0.38) KDM4ECA12CA1CA2TP53
SCHEMBL23596132 0.84 PLA2G2A (0.42) KDM4ECA12CA1CA2TP53
SCHEMBL13084918 0.84 ALDH1A1 (0.58) KDM4ECA12CA1CA2TP53
SCHEMBL23596031 0.82 ALDH1A1 (0.42) KDM4ECA12CA1CA2TP53
SCHEMBL23596610 0.80 PTGS2 (0.37) KDM4ECA12CA1CA2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105051911-A Excitonic energy transfer to increase inorganic solar cell efficiency UNIV SOUTHERN CALIFORNIA 2015-11-11 CN disclosed