Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 9/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28018947 | 0.84 | RIPK1 (0.49) | RIPK1HSP90AA1P2RX7 | |
| SCHEMBL1580110 | 0.77 | ABHD6 (0.55) | RIPK1POLBMEN1TSHRHTT | |
| SCHEMBL13093649 | 0.77 | POLB (0.55) | RIPK1POLBMEN1TSHRHTT | |
| SCHEMBL16510056 | 0.75 | POLB (0.60) | RIPK1POLBMEN1TSHRHTT | |
| SCHEMBL24011067 | 0.74 | RIPK1 (0.68) | RIPK1POLBMEN1TSHRHTT | |
| SCHEMBL28685326 | 0.74 | ALDH1A1 (0.49) | RIPK1POLB | |
| SCHEMBL18711396 | 0.74 | POLB (0.61) | RIPK1POLBMEN1TSHRHTT | |
| SCHEMBL27488566 | 0.74 | RIPK1 (0.51) | RIPK1 | |
| SCHEMBL27801641 | 0.73 | SLC6A2 (0.46) | RIPK1CYP2C19 | |
| SCHEMBL27668157 | 0.73 | RIPK1 (0.45) | RIPK1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104703973-A | Substituted phenyl carbamate compounds | HOFFMANN LA ROCHE | 2015-06-10 | — | — | CN | disclosed |