2-Mercaptobenzothiazole

2-Mercaptobenzothiazole

SCHEMBL28019016

CC(C)=O.Sc1nc2ccccc2s1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 1/20 0.56
DYRK1A Q13627 1/20 0.56
CYP1A2 P05177 2/20 0.53
GAA P10253 1/20 0.53
ALDH1A1 P00352 3/20 0.51
MAPT P10636 2/20 0.51
CYP2C19 P33261 1/20 0.51
DDAH1 O94760 1/20 0.49
ALOX15 P16050 2/20 0.47
TSHR P16473 2/20 0.47
LMNA P02545 2/20 0.47
CASP1 P29466 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
NPC1 O15118 6/20 0.46
RAB9A P51151 6/20 0.46
SMN1; SMN2 Q16637 5/20 0.46
TP53 P04637 1/20 0.46
CASP3 P42574 1/20 0.46
SENP8 Q96LD8 1/20 0.46
SENP7 Q9BQF6 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Mercaptobenzothiazole SCHEMBL27994442 0.95 ADORA1 (0.54) ADORA1DYRK1ACYP1A2GAAALDH1A1
2-Mercaptobenzothiazole SCHEMBL28760767 0.89 ALDH1A1 (0.50) ADORA1DYRK1ACYP1A2GAAALDH1A1
2-Mercaptobenzothiazole SCHEMBL8965658 0.89 ADORA1 (0.49) ADORA1DYRK1ACYP1A2GAAALDH1A1
2-Mercaptobenzothiazole SCHEMBL29509878 0.88 ALDH1A1 (0.54) CYP1A2GAAALDH1A1MAPTCYP2C19
2-Mercaptobenzothiazole SCHEMBL3789760 0.88 ALDH1A1 (0.54) CYP1A2GAAALDH1A1MAPTCYP2C19
2-Mercaptobenzothiazole SCHEMBL23237 0.88 ALDH1A1 (0.54) CYP1A2GAAALDH1A1MAPTCYP2C19
2-Mercaptobenzothiazole SCHEMBL10595021 0.87 KMT2A (0.49) ADORA1DYRK1AGAAALDH1A1MAPT
2-Mercaptobenzothiazole SCHEMBL28495949 0.87 ALDH1A1 (0.46) ADORA1DYRK1ACYP1A2GAAALDH1A1
2-Mercaptobenzothiazole SCHEMBL28119033 0.87 ALDH1A1 (0.46) ADORA1DYRK1ACYP1A2GAAALDH1A1
2-Mercaptobenzothiazole SCHEMBL3799827 0.86 PSMB8 (0.48) ADORA1DYRK1ACYP1A2GAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105061357-A 2-mercaptobenzothiazole refining method UNIV QINGDAO SCIENCE & TECHNOLOGY 2015-11-18 CN claimed
CN-117534996-A High-strength wear-resistant aluminum alloy template and surface treatment process thereof 上海衡硕装饰设计工程有限公司 2024-02-09 CN disclosed
CN-111424180-B Method for recovering gold from gold-loaded carbon in thiosulfate system 昆明理工大学 2021-11-12 CN disclosed
CN-111424180-A Method for recovering gold from gold-loaded carbon in thiosulfate system 昆明理工大学 2020-07-17 CN disclosed