2-Mercaptobenzothiazole

2-Mercaptobenzothiazole

SCHEMBL8965658

C=C(C)C(=O)O.Sc1nc2ccccc2s1

nearest known ligand 0.49

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 1/20 0.49
DYRK1A Q13627 1/20 0.49
GAA P10253 3/20 0.47
CYP1A2 P05177 2/20 0.47
MAPT P10636 2/20 0.46
CYP2C19 P33261 1/20 0.46
ALDH1A1 P00352 4/20 0.45
RAB9A P51151 6/20 0.44
SMN1; SMN2 Q16637 6/20 0.44
NPC1 O15118 5/20 0.44
LMNA P02545 2/20 0.44
TP53 P04637 1/20 0.44
CASP3 P42574 1/20 0.44
SENP8 Q96LD8 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
SENP6 Q9GZR1 1/20 0.44
THRB P10828 1/20 0.44
RECQL P46063 1/20 0.44
NFKB1 P19838 2/20 0.43
NFKB2 Q00653 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Mercaptobenzothiazole SCHEMBL27994442 0.90 ADORA1 (0.54) ADORA1DYRK1AGAACYP1A2MAPT
2-Mercaptobenzothiazole SCHEMBL28019016 0.89 ADORA1 (0.56) ADORA1DYRK1AGAACYP1A2MAPT
2-Mercaptobenzothiazole SCHEMBL10595021 0.83 KMT2A (0.49) ADORA1DYRK1AGAAMAPTALDH1A1
2-Mercaptobenzothiazole SCHEMBL27074383 0.83 PSMB8 (0.48) ADORA1DYRK1ACYP1A2MAPTCYP2C19
2-Mercaptobenzothiazole SCHEMBL28866073 0.83 ALDH1A1 (0.52) GAACYP1A2MAPTCYP2C19ALDH1A1
2-Mercaptobenzothiazole SCHEMBL1041771 0.83 SMN1; SMN2 (0.54) ADORA1DYRK1AGAACYP1A2MAPT
2-Mercaptobenzothiazole SCHEMBL28760767 0.82 ALDH1A1 (0.50) ADORA1DYRK1AGAACYP1A2MAPT
2-Mercaptobenzothiazole SCHEMBL29509878 0.81 ALDH1A1 (0.54) GAACYP1A2MAPTCYP2C19ALDH1A1
2-Mercaptobenzothiazole SCHEMBL23237 0.81 ALDH1A1 (0.54) GAACYP1A2MAPTCYP2C19ALDH1A1
2-Mercaptobenzothiazole SCHEMBL3789760 0.81 ALDH1A1 (0.54) GAACYP1A2MAPTCYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104212549-A Oxidation corrosion-resistant nanometer aluminum nitride transformer oil containing pine tar, and preparation method thereof TONGLING RIKE ELECTRONICS CO LTD 2014-12-17 CN disclosed
EP-0490269-B1 Graft copolymer and process for producing the same IDEMITSU KOSAN CO (JP) 1996-02-28 EP disclosed
US-5250629-A Graft polymerization of styrene and ethylenically unsaturated monomer using transition metal catalysts, organoaluminum compounds; films, packaging, automobile parts IDEMITSU KOSAN CO., LTD. (JP) 1993-10-05 US disclosed
EP-0490269-A1 Graft copolymer and process for producing the same IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-06-17 EP disclosed
US-4576870-A ACRYLIC POLYMER AS UV ABSORBER ROHM GMBH (DE) 1986-03-18 US disclosed