Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 8/20 | 0.54 |
| ▸ | ICMT | O60725 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 6/20 | 0.38 |
| ▸ | CNR2 | P34972 | 6/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28019125 | 0.99 | KCNH2 (0.55) | KCNH2ICMTCYP11B2SIGMAR1NOTUM | |
| SCHEMBL28018610 | 0.96 | KCNH2 (0.58) | KCNH2ICMTCYP11B2NOTUM | |
| SCHEMBL27736888 | 0.82 | KCNH2 (0.48) | KCNH2ICMT | |
| SCHEMBL11264432 | 0.77 | ICMT (0.45) | ICMT | |
| SCHEMBL27736887 | 0.76 | KDR (0.43) | KCNH2ICMTNOTUM | |
| SCHEMBL27736893 | 0.75 | ICMT (0.46) | ICMT | |
| SCHEMBL28779311 | 0.75 | ICMT (0.41) | KCNH2ICMT | |
| SCHEMBL25100064 | 0.74 | TNK2 (0.41) | ICMTCNR1 | |
| SCHEMBL27736899 | 0.74 | ICMT (0.41) | KCNH2ICMT | |
| SCHEMBL27837718 | 0.72 | ICMT (0.40) | KCNH2ICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104619323-A | A3 adenosine receptor ligands for use in treatment of a sexual dysfunction | CAN FITE BIOPHARMA LTD | 2015-05-13 | — | — | CN | claimed |
| CN-104619323-A | A3 adenosine receptor ligands for use in treatment of a sexual dysfunction | CAN FITE BIOPHARMA LTD | 2015-05-13 | — | — | CN | disclosed |