Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TNK2 | Q07912 | 4/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27736893 | 0.98 | ICMT (0.46) | ICMTNPC1RAB9AMAPK1TNK2 | |
| SCHEMBL28779311 | 0.84 | ICMT (0.41) | ICMTTNK2TLR7ALDH1A1GFER | |
| SCHEMBL13117192 | 0.84 | ICMT (0.46) | ICMTNPC1RAB9ATNK2HRH1 | |
| SCHEMBL27736888 | 0.82 | KCNH2 (0.48) | ICMTMAPK1TNK2TSHRDRD1 | |
| SCHEMBL27736887 | 0.82 | KDR (0.43) | ICMTTNK2KDM4ECYP1A2CYP3A4 | |
| SCHEMBL27837718 | 0.81 | ICMT (0.40) | ICMTTNK2ALDH1A1APOBEC3GFGFR2 | |
| SCHEMBL25100064 | 0.80 | TNK2 (0.41) | ICMTNPC1RAB9ATNK2LMNA | |
| SCHEMBL28019124 | 0.77 | KCNH2 (0.54) | ICMT | |
| SCHEMBL27736889 | 0.77 | ICMT (0.49) | ICMTRAB9AATM | |
| SCHEMBL28019125 | 0.75 | KCNH2 (0.55) | ICMTCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4340744-A | METAL OXIDES AS CATALYSTS | BASF AKTIENGESELLSCHAFT (DE) | 1982-07-20 | — | — | US | disclosed |
| EP-0036129-A1 | Process for the preparation of imidazoles | BASF Aktiengesellschaft (DE) | 1981-09-23 | — | — | EP | disclosed |
| EP-0000208-B1 | PROCESS FOR THE PREPARATION OF IMIDAZOLES | BASF Aktiengesellschaft (DE) | 1980-04-30 | — | — | EP | disclosed |
| EP-0000208-A1 | Process for the preparation of imidazoles | BASF Aktiengesellschaft (DE) | 1979-01-10 | — | — | EP | disclosed |