Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28013575 | 0.82 | TP53 (0.50) | PPIAALDH1A1MAPTL3MBTL1HTT | |
| SCHEMBL28013536 | 0.81 | PPIA (0.52) | PPIAALDH1A1NPC1HPGDGAA | |
| SCHEMBL28819014 | 0.79 | HTT (0.53) | PPIAALDH1A1MAPTL3MBTL1HTT | |
| SCHEMBL28019226 | 0.75 | CHRM1 (0.41) | PPIAALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL28013540 | 0.73 | CHRM1 (0.49) | PPIAALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL28014318 | 0.73 | ALDH1A1 (0.53) | ALDH1A1NPC1L3MBTL1HTTGAA | |
| SCHEMBL28014189 | 0.72 | L3MBTL1 (0.43) | ALDH1A1L3MBTL1GAAMEN1KMT2A | |
| SCHEMBL2113823 | 0.71 | NPC1 (0.59) | ALDH1A1NPC1MAPTHPGDL3MBTL1 | |
| SCHEMBL7160814 | 0.69 | CYP3A4 (0.53) | ALDH1A1NPC1MAPTHPGDL3MBTL1 | |
| SCHEMBL269331 | 0.69 | NPC1 (0.60) | ALDH1A1NPC1HPGDL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104610142-A | 3-bishydrazide diphenylurea derivative, and preparation method and application of 3-bishydrazide diphenylurea derivative | UNIV QINGDAO AGRICULTURAL | 2015-05-13 | — | — | CN | disclosed |