Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CDK4 | P11802 | 2/20 | 0.46 |
| ▸ | CCND1 | P24385 | 2/20 | 0.46 |
| ▸ | PPIA | P62937 | 4/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.42 |
| ▸ | TUBB | P07437 | 2/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.42 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.42 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.42 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28014318 | 0.84 | ALDH1A1 (0.53) | HTTCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL28013575 | 0.84 | TP53 (0.50) | HTTMAPTPPIATP53ALDH1A1 | |
| SCHEMBL28019221 | 0.79 | PPIA (0.49) | HTTMAPTPPIAALDH1A1L3MBTL1 | |
| SCHEMBL28013540 | 0.79 | CHRM1 (0.49) | MAPTPPIAALDH1A1 | |
| SCHEMBL975433 | 0.79 | HTT (0.62) | HTTMAPTCDK4CCND1TUBB4A | |
| SCHEMBL28019226 | 0.78 | CHRM1 (0.41) | MAPTPPIATP53CHRNB2CHRNB4 | |
| SCHEMBL28014189 | 0.76 | L3MBTL1 (0.43) | CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1 | |
| SCHEMBL29818012 | 0.75 | BCAT2 (0.65) | HTTMAPTCDK4CCND1TUBB4A | |
| SCHEMBL3632646 | 0.75 | BCAT2 (0.65) | HTTMAPTCDK4CCND1TUBB4A | |
| SCHEMBL6300626 | 0.74 | HTT (0.72) | HTTMAPTTP53CHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104592059-B | 3-acylhydrazone diphenylurea derivative and its preparation method and application | 青岛农业大学 | 2016-07-06 | — | — | CN | disclosed |
| CN-104592059-A | 3-acylhydrazone diphenylurea derivatives as well as preparation method and applications thereof | UNIV QINGDAO AGRICULTURAL | 2015-05-06 | — | — | CN | disclosed |