Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.71 |
| ▸ | THRA | P10827 | 1/20 | 0.71 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.70 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.59 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28019282 | 0.98 | THRB (0.69) | THRBTHRASMPD1PLA2G4BKMT2A | |
| SCHEMBL15474092 | 0.94 | THRB (0.63) | THRBTHRASMPD1PLA2G4BKMT2A | |
| SCHEMBL27586299 | 0.90 | THRA (0.78) | THRBTHRASMPD1PLA2G4BKMT2A | |
| SCHEMBL14176561 | 0.89 | THRB (0.59) | THRBTHRASMPD1PLA2G4BKMT2A | |
| SCHEMBL27812355 | 0.89 | KMT2A (0.73) | THRBTHRASMPD1PLA2G4BKMT2A | |
| SCHEMBL5312197 | 0.88 | THRB (0.68) | THRBTHRASMPD1PLA2G4BKMT2A | |
| SCHEMBL27626399 | 0.88 | KMT2A (0.59) | THRBTHRASMPD1PLA2G4BKMT2A | |
| SCHEMBL2887568 | 0.88 | KMT2A (0.82) | THRBTHRASMPD1PLA2G4BKMT2A | |
| SCHEMBL16196481 | 0.88 | SMPD1 (0.74) | THRBTHRASMPD1PLA2G4BKMT2A | |
| SCHEMBL7047692 | 0.88 | KMT2A (0.82) | THRBTHRASMPD1PLA2G4BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104822666-B | Terazololine-one compound and application thereof | 住友化学株式会社 | 2016-09-21 | — | — | CN | disclosed |
| CN-104822666-A | Tetrazolinone compound and use thereof | SUMITOMO CHEMICAL CO | 2015-08-05 | — | — | CN | disclosed |