SCHEMBL7047692

SCHEMBL7047692

CCCCCCCOc1cccc(C(=O)O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.82
PLA2G4B P0C869 3/20 0.82
SMPD1 P17405 3/20 0.74
PLA2G2A P14555 1/20 0.73
NR1H4 Q96RI1 2/20 0.73
TP53 P04637 1/20 0.69
TSHR P16473 1/20 0.69
PTPN11 Q06124 1/20 0.67
THRA P10827 1/20 0.67
THRB P10828 1/20 0.67
RARB P10826 3/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31661137 1.00 KMT2A (0.82) KMT2APLA2G4BSMPD1PLA2G2ANR1H4
SCHEMBL4652291 1.00 KMT2A (0.82) KMT2APLA2G4BSMPD1PLA2G2ANR1H4
SCHEMBL8080220 1.00 KMT2A (0.82) KMT2APLA2G4BSMPD1PLA2G2ANR1H4
SCHEMBL15766225 1.00 KMT2A (0.82) KMT2APLA2G4BSMPD1PLA2G2ANR1H4
SCHEMBL7822821 1.00 KMT2A (0.82) KMT2APLA2G4BSMPD1PLA2G2ANR1H4
SCHEMBL8081150 1.00 KMT2A (0.82) KMT2APLA2G4BSMPD1PLA2G2ANR1H4
SCHEMBL8082044 1.00 KMT2A (0.82) KMT2APLA2G4BSMPD1PLA2G2ANR1H4
SCHEMBL8086388 1.00 KMT2A (0.82) KMT2APLA2G4BSMPD1PLA2G2ANR1H4
SCHEMBL2887568 1.00 KMT2A (0.82) KMT2APLA2G4BSMPD1PLA2G2ANR1H4
SCHEMBL29758526 1.00 KMT2A (0.82) KMT2APLA2G4BSMPD1PLA2G2ANR1H4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016058991-A1 POLYMERS FEATURING ENHANCED FLOW SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2016-04-21 WO claimed
JP-7258170-A None JP disclosed
US-11446398-B2 Regulated biocircuit systems OBSIDIAN THERAPEUTICS, INC. (US) 2022-09-20 US disclosed
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed
US-20190192691-A1 REGULATED BIOCIRCUIT SYSTEMS OBSIDIAN THERAPEUTICS, INC. 2019-06-27 US disclosed
WO-2018204764-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION (US) 2018-11-08 WO disclosed
US-9475750-B2 Phenylketone carboxylate compounds and pharmaceutical uses thereof PROMETIC BIOSCIENCES INC. (CA) 2016-10-25 US disclosed
US-9439882-B2 Compounds and compositions for the treatment of cancer PROMETIC BIOSCIENCES INC. (CA) 2016-09-13 US disclosed
WO-2016058991-A1 POLYMERS FEATURING ENHANCED FLOW SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2016-04-21 WO disclosed
US-20150313856-A1 COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CANCER PROMETIC PHARMA SMT LIMITED (GB) 2015-11-05 US disclosed
EP-0676652-A2 Optical compensatory sheet and liquid crystal display FUJI PHOTO FILM CO., LTD. (JP) 1995-10-11 EP disclosed
JP-H07258170-A NOVEL TRIPHENYLENE DERIVATIVE FUJI PHOTO FILM CO LTD 1995-10-09 JP disclosed
US-5385917-A Treating androgen dependent diseases MITSUBISHI KASEI CORPORATION (JP) 1995-01-31 US disclosed
EP-0579223-A1 Carboxylic acid derivatives having 5 alpha-reductase inhibitory activity Mitsubishi Chemical Corporation (JP) 1994-01-19 EP disclosed
US-5140046-A Slow reacting substance of anaphylaxis antagonists YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1992-08-18 US disclosed
US-5116853-A SRS-Antagonist, Antiallergens MASE TOSHIYASU (JP) 1992-05-26 US disclosed
EP-0425134-A1 Condensed pyrrolo derivatives, process for their preparation and pharmaceutical compositions containing them YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1991-05-02 EP disclosed
US-4994479-A Antagonists of SRS-A(slow reacting substance of anaphylaxis); antiallergens, antiischemic agents YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1991-02-19 US disclosed
EP-0218728-A1 PHENYLENE DERIVATIVES YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1987-04-22 EP disclosed
WO-1986005779-A1 PHENYLENE DERIVATIVES YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1986-10-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150313856-A1 COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CANCER DCK, TOP2B, TOP2A KMT2A 1361/4885PLA2G4B 3993/4885SMPD1 2799/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.