⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28820158 | 0.85 | — | — | |
| SCHEMBL8520734 | 0.76 | PRCP (0.36) | — | |
| SCHEMBL11013331 | 0.75 | CHRNB2 (0.30) | — | |
| SCHEMBL11517818 | 0.75 | CHRNB2 (0.37) | — | |
| SCHEMBL29955921 | 0.69 | PRCP (0.35) | — | |
| SCHEMBL18602953 | 0.68 | — | — | |
| SCHEMBL25021692 | 0.67 | CHRM5 (0.31) | — | |
| SCHEMBL8720595 | 0.67 | ACE (0.36) | — | |
| SCHEMBL3355254 | 0.66 | OPRD1 (0.42) | — | |
| SCHEMBL19688688 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104640856-B | Carbazole-containing sulfonamides as cryptochrome modulators | 复位治疗公司 | 2017-09-15 | — | — | CN | disclosed |
| CN-104640856-A | Carbazole-containing sulfonamides as cryptochrome modulators | RESET THERAPEUTICS INC | 2015-05-20 | — | — | CN | disclosed |