Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18602953 | 0.94 | — | — | |
| SCHEMBL15383931 | 0.81 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL8520734 | 0.81 | PRCP (0.36) | CHRNB2CHRNA7CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL27541668 | 0.81 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL11062031 | 0.81 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL11013331 | 0.79 | CHRNB2 (0.30) | CHRNB2CHRNA7CHRNA4CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL27491495 | 0.79 | CXCR4 (0.34) | ALDH1A1 | |
| SCHEMBL26187447 | 0.78 | LMNA (0.34) | — | |
| SCHEMBL27772503 | 0.76 | CHRNB2 (0.49) | CHRNB2CHRNA7CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL28019642 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180071306-A1 | CARBAZOLE-CONTAINING SULFONAMIDES AS CRYPTOCHROME MODULATORS | Synchronicity Pharma, Inc. | 2018-03-15 | — | — | US | disclosed |
| US-9775845-B2 | Carbazole-containing sulfonamides as cryptochrome modulators | RESET THERAPEUTICS, INC. (US) | 2017-10-03 | — | — | US | disclosed |
| US-20160200732-A1 | CARBAZOLE-CONTAINING SULFONAMIDES AS CRYPTOCHROME MODULATORS | Synchronicity Pharma, Inc. | 2016-07-14 | — | — | US | disclosed |
| US-9265772-B2 | Carbazole-containing sulfonamides as cryptochrome modulators | RESET THERAPEUTICS, INC. (US) | 2016-02-23 | — | — | US | disclosed |
| US-20130303524-A1 | Carbazole-Containing Sulfonamides as Cryptochrome Modulators | Synchronicity Pharma, Inc. | 2013-11-14 | — | — | US | disclosed |
| US-4172180-A | BASIC POLYMER WHICH REACTS WITH HYDROGEN HALIDE AND IS CAPABLE OF FORMING QUATERNARY SALT, AND HALOGEN CONTAINING POLYMER CAPABLE OF FORMING CONJUGATED POLYENE BY ELIMINATION OF HYDROGEN HALIDE | FUJI PHOTO FILM CO., LTD. (JP) | 1979-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303524-A1 | Carbazole-Containing Sulfonamides as Cryptochrome Modulators | CRY1, CRY2, CRYAB | CHRNB2 1380/4885CHRNA7 1306/4885CHRNA4 1807/4885 |
| US-20160200732-A1 | CARBAZOLE-CONTAINING SULFONAMIDES AS CRYPTOCHROME MODULATORS | CRY1, CRY2, CRYAB | CHRNB2 1386/4885CHRNA7 1252/4885CHRNA4 1810/4885 |
| US-20180071306-A1 | CARBAZOLE-CONTAINING SULFONAMIDES AS CRYPTOCHROME MODULATORS | CRY1, CRY2, CRYAB | CHRNB2 1386/4885CHRNA7 1252/4885CHRNA4 1810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.