Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 2/20 | 0.32 |
| ▸ | PRKCG | P05129 | 2/20 | 0.32 |
| ▸ | PRKCB | P05771 | 2/20 | 0.32 |
| ▸ | PRKCA | P17252 | 2/20 | 0.32 |
| ▸ | PRKACA | P17612 | 2/20 | 0.32 |
| ▸ | PRKACG | P22612 | 2/20 | 0.32 |
| ▸ | PRKACB | P22694 | 2/20 | 0.32 |
| ▸ | PRKCH | P24723 | 2/20 | 0.32 |
| ▸ | PRKCI | P41743 | 2/20 | 0.32 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.32 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.32 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.32 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1505813 | 0.78 | LMNA (0.31) | HTTLMNA | |
| SCHEMBL2456274 | 0.78 | LMNA (0.31) | HTTLMNA | |
| SCHEMBL2309048 | 0.78 | LMNA (0.31) | HTTLMNA | |
| Hydrochloric Acid SCHEMBL31094833 | 0.76 | LMNA (0.33) | PRKD3PRKCGPRKCBPRKCAPRKACA | |
| SCHEMBL21214402 | 0.70 | — | — | |
| SCHEMBL27862771 | 0.70 | — | — | |
| SCHEMBL28301594 | 0.70 | — | — | |
| Trifluoroacetic Acid SCHEMBL28724275 | 0.69 | PKM (0.35) | — | |
| Trifluoroacetic Acid SCHEMBL28058829 | 0.69 | PKM (0.35) | — | |
| SCHEMBL12583134 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104822681-B | Pyrazolopyrimidine compound as kinase inhibitor | 普林斯匹亚生物制药公司 | 2018-01-30 | — | — | CN | disclosed |
| CN-104822681-A | Pyrazolopyrimidine compounds as kinase inhibitors | PRINCIPIA BIOPHARMA INC | 2015-08-05 | — | — | CN | disclosed |