Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 6/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | FABP6 | P51161 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10966821 | 0.79 | FABP6 (0.47) | NR3C2NOTUMFABP6KDM4EALDH1A1 | |
| SCHEMBL429962 | 0.78 | MAOB (0.42) | NOTUMKDM4ECYP1A2MEN1NPC1 | |
| SCHEMBL11926931 | 0.78 | MMP12 (0.49) | NR3C2ALDH1A1GAACYP1A2MEN1 | |
| SCHEMBL1758974 | 0.78 | APP (0.42) | L3MBTL1CYP1A2PKMCYP19A1MAPT | |
| SCHEMBL3962887 | 0.74 | CYP1A2 (0.54) | ALDH1A1CYP1A2NPC1PKMRAB9A | |
| SCHEMBL30450885 | 0.74 | CYP1A2 (0.54) | ALDH1A1CYP1A2NPC1PKMRAB9A | |
| SCHEMBL7304831 | 0.74 | MAPT (0.56) | KDM4EALDH1A1GAANPC1RAB9A | |
| SCHEMBL4290047 | 0.73 | MAOA (0.45) | FABP6 | |
| SCHEMBL3346103 | 0.73 | TDP2 (0.44) | ALDH1A1GAACYP1A2MEN1NPC1 | |
| SCHEMBL7675061 | 0.71 | MAOA (0.46) | NOTUMFABP6KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104829575-A | Preparation method of 6-fluoropyran derivative | Hunan huateng pharmaceutical co ltd | 2015-08-12 | — | — | CN | disclosed |