Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28019670 | 0.90 | TYR (0.45) | TYR | |
| SCHEMBL1983988 | 0.85 | TYR (0.44) | TYRSLC9A1CYP3A4CYP2C9 | |
| SCHEMBL28820116 | 0.83 | TYR (0.43) | TYRTRPC6 | |
| SCHEMBL27623434 | 0.82 | NPC1 (0.44) | GRM5SLC9A1CYP3A4CYP2C9CYP2C19 | |
| Phenethylamine SCHEMBL28020211 | 0.81 | TYR (0.50) | TYR | |
| SCHEMBL2474909 | 0.81 | ALDH1A1 (0.56) | SMN1; SMN2 | |
| SCHEMBL25429337 | 0.77 | SLC9A1 (0.40) | SLC9A1 | |
| SCHEMBL2474344 | 0.77 | GRIN1 (0.42) | TYRSMN1; SMN2 | |
| SCHEMBL13504462 | 0.77 | KCNH2 (0.43) | TYRSLC9A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13504458 | 0.77 | KCNH2 (0.43) | TYRSLC9A1CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104666299-A | 4-(azacycloalkyl)benzene-1,3-diol compounds as tyrosinase inhibitors, process for the preparation thereof and use thereof | GALDERMA RES & DEV | 2015-06-03 | — | — | CN | disclosed |