Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28020159 | 0.83 | TYR (0.45) | TYRTRPC6 | |
| Phenethylamine SCHEMBL28020211 | 0.83 | TYR (0.50) | TYR | |
| SCHEMBL28019670 | 0.83 | TYR (0.45) | TYRTMEM97SIGMAR1 | |
| SCHEMBL1983988 | 0.82 | TYR (0.44) | TYRALDH1A1MGLL | |
| SCHEMBL2478169 | 0.80 | ADRB1 (0.45) | ALDH1A1MAPK1 | |
| SCHEMBL25429337 | 0.77 | SLC9A1 (0.40) | PARP10MGLL | |
| SCHEMBL27623434 | 0.74 | NPC1 (0.44) | — | |
| SCHEMBL2474344 | 0.74 | GRIN1 (0.42) | TYRALDH1A1MGLL | |
| SCHEMBL2474460 | 0.74 | MGLL (0.58) | MGLL | |
| SCHEMBL16564477 | 0.74 | MAOB (0.40) | TYRALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104666299-A | 4-(azacycloalkyl)benzene-1,3-diol compounds as tyrosinase inhibitors, process for the preparation thereof and use thereof | GALDERMA RES & DEV | 2015-06-03 | — | — | CN | disclosed |