SCHEMBL28020180

SCHEMBL28020180

O=C(O)C1(C(=O)O)C=CC(c2cccc(O)c2O)=CC1

nearest known ligand 0.31

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.31
HPGD P15428 3/20 0.31
ALOX15 P16050 3/20 0.31
RECQL P46063 3/20 0.31
HSD17B10 Q99714 3/20 0.31
TDP1 Q9NUW8 3/20 0.31
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
LMNA P02545 2/20 0.31
ADAMTS4 O75173 1/20 0.31
EGFR P00533 1/20 0.31
FYN P06241 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31
CA6 P23280 1/20 0.31
CDK2 P24941 1/20 0.31
MMP12 P39900 1/20 0.31
ADAMTS5 Q9UNA0 1/20 0.31
CA12 O43570 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27593702 0.78 ALDH1A1 (0.35) ALDH1A1HPGDALOX15RECQLHSD17B10
SCHEMBL8775987 0.78 MYC (0.33) ALDH1A1TDP1CA1CA2LMNA
SCHEMBL6332668 0.78 LIG1 (0.38) ALDH1A1ALOX15HSD17B10CA1CA2
SCHEMBL28131668 0.78 MCL1 (0.37) HPGDTDP1THRBTP53TTR
SCHEMBL27865152 0.78 THRB (0.32) TDP1THRB
SCHEMBL28198344 0.78 ALDH1A1 (0.35) ALDH1A1HSD17B10TDP1KDM4EMEN1
SCHEMBL27761664 0.77 HPGD (0.34) ALDH1A1HPGDALOX15RECQLHSD17B10
SCHEMBL28009197 0.75 MIF (0.33) ALDH1A1HPGDALOX15RECQLHSD17B10
SCHEMBL316146 0.74 THRB (0.32) TDP1THRBTP53
SCHEMBL27741185 0.74 ALDH1A1 (0.40) ALDH1A1HPGDTDP1LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108456218-B Rare earth-organic porous material, preparation method thereof and application thereof in detection of neurological disease marker glutamic acid 浙江大学 2020-03-17 CN disclosed
CN-104726237-A Yellow-spot-removing dry cleaning agent SHANGHAI PENGGANG IND DEV CO LTD 2015-06-24 CN disclosed