Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28773794 | 0.83 | ALDH1A1 (0.36) | ALDH1A1HSD17B10THRBTDP1MAPT | |
| SCHEMBL28131668 | 0.82 | MCL1 (0.37) | THRBTDP1MCL1 | |
| SCHEMBL27865152 | 0.82 | THRB (0.32) | THRBTDP1 | |
| SCHEMBL316146 | 0.79 | THRB (0.32) | THRBTDP1MCL1 | |
| SCHEMBL27741185 | 0.78 | ALDH1A1 (0.40) | ALDH1A1TDP1MAPTKDM4ENPSR1 | |
| SCHEMBL28020180 | 0.78 | ALDH1A1 (0.31) | ALDH1A1HSD17B10THRBTDP1MAPT | |
| SCHEMBL21328421 | 0.78 | THRB (0.32) | THRBTDP1 | |
| Hydrochloric Acid SCHEMBL2219432 | 0.78 | THRB (0.32) | THRBTDP1 | |
| SCHEMBL28256376 | 0.78 | THRB (0.32) | THRBTDP1 | |
| SCHEMBL27992139 | 0.78 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1HSD17B10TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104667876-B | Serial MOF types multilevel hole material IPD mesoMOF 1~8 and preparation method thereof, and the adjusting method of mesoporous size | 北京思达安新材料科技有限公司 | 2018-02-13 | — | — | CN | disclosed |