Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.63 |
| ▸ | GAA | P10253 | 6/20 | 0.63 |
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | CTSD | P07339 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6454614 | 0.85 | ALDH1A1 (0.81) | NPC1RAB9AALDH1A1GAAMAPT | |
| SCHEMBL20984065 | 0.78 | GAA (0.67) | ALDH1A1GAAMAPTPOLBMAOA | |
| SCHEMBL3267559 | 0.77 | GAA (0.69) | NPC1RAB9AALDH1A1GAAMAPT | |
| SCHEMBL5226740 | 0.77 | KCNMA1 (0.67) | NPC1RAB9AALDH1A1GAAMAPT | |
| SCHEMBL6654129 | 0.76 | MAPT (0.58) | NPC1RAB9AALDH1A1GAAMAPT | |
| SCHEMBL11207257 | 0.75 | ALDH1A1 (0.63) | RAB9AALDH1A1GAAMAPTPOLB | |
| SCHEMBL10433483 | 0.74 | ALDH1A1 (0.63) | ALDH1A1GAAMAPTPOLBMAOA | |
| SCHEMBL2937028 | 0.74 | ALDH1A1 (0.68) | NPC1RAB9AALDH1A1GAAMAPT | |
| SCHEMBL6450415 | 0.74 | ALDH1A1 (0.70) | NPC1RAB9AALDH1A1GAAMAPT | |
| SCHEMBL5237553 | 0.74 | KCNMA1 (0.58) | NPC1RAB9AALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104768952-A | PI3K inhibitors | KBP BIOSCIENCES CO LTD | 2015-07-08 | — | — | CN | disclosed |