Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | PPID | Q08752 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28020432 | 1.00 | LMNA (0.45) | LMNARAB9ATP53CA12CA1 | |
| SCHEMBL28020416 | 0.83 | PPID (0.50) | HPGDKMT2ASMN1; SMN2ALDH1A1PPID | |
| SCHEMBL28020411 | 0.83 | PPID (0.50) | HPGDKMT2ASMN1; SMN2ALDH1A1PPID | |
| SCHEMBL28019981 | 0.82 | CYP2C9 (0.50) | LMNARAB9ATP53RIPK1HPGD | |
| SCHEMBL28019983 | 0.82 | CYP2C9 (0.50) | LMNARAB9ATP53RIPK1HPGD | |
| SCHEMBL28020080 | 0.82 | KMT2A (0.48) | RAB9ATP53CA12CA1CA7 | |
| SCHEMBL28020076 | 0.82 | KMT2A (0.48) | RAB9ATP53CA12CA1CA7 | |
| SCHEMBL28820146 | 0.80 | KMT2A (0.46) | CA12CA1CA7CA14HPGD | |
| SCHEMBL28820145 | 0.80 | KMT2A (0.46) | CA12CA1CA7CA14HPGD | |
| Acetic Acid SCHEMBL7982271 | 0.74 | CA12 (0.60) | LMNARAB9ACA12CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103910644-B | Beta-enaminone ester compounds, and synthesis method and application of beta-enaminone ester compounds | UNIV GUANGXI NORMAL | 2015-06-24 | — | — | CN | disclosed |