Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28820145 | 1.00 | KMT2A (0.46) | KMT2AMEN1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL28020416 | 0.86 | PPID (0.50) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL28020411 | 0.86 | PPID (0.50) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL28020080 | 0.85 | KMT2A (0.48) | KMT2AMEN1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL28020076 | 0.85 | KMT2A (0.48) | KMT2AMEN1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL28019983 | 0.80 | CYP2C9 (0.50) | KMT2AMEN1MAPTALDH1A1HDAC1 | |
| SCHEMBL28019981 | 0.80 | CYP2C9 (0.50) | KMT2AMEN1MAPTALDH1A1HDAC1 | |
| SCHEMBL28020432 | 0.80 | LMNA (0.45) | KMT2AALDH1A1CA12CA1CA7 | |
| SCHEMBL28020429 | 0.80 | LMNA (0.45) | KMT2AALDH1A1CA12CA1CA7 | |
| SCHEMBL6237639 | 0.75 | ALDH1A1 (0.57) | KMT2AMEN1MAPTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103910644-B | Beta-enaminone ester compounds, and synthesis method and application of beta-enaminone ester compounds | UNIV GUANGXI NORMAL | 2015-06-24 | — | — | CN | disclosed |