Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 11/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27729038 | 0.82 | F10 (0.39) | F10TP53MEN1KMT2ACYP11B1 | |
| SCHEMBL28020833 | 0.74 | F10 (0.44) | F10TP53MEN1KMT2ALMNA | |
| SCHEMBL611715 | 0.66 | F10 (0.57) | F10TP53MEN1KMT2ALMNA | |
| SCHEMBL608919 | 0.65 | F10 (0.58) | F10TP53MEN1KMT2AHTT | |
| SCHEMBL8136067 | 0.65 | TP53 (0.48) | F10TP53HTT | |
| SCHEMBL24262954 | 0.64 | F10 (0.48) | F10TP53KMT2ALMNAHTT | |
| SCHEMBL1922766 | 0.63 | TP53 (0.49) | F10TP53MEN1KMT2AHTT | |
| SCHEMBL13660064 | 0.62 | MAPT (0.51) | F10TP53CYP11B1CYP11B2LMNA | |
| SCHEMBL2191827 | 0.62 | CRHR1 (0.57) | TP53MEN1KMT2AHTTMAPT | |
| SCHEMBL11119022 | 0.62 | HTT (0.55) | TP53LMNAHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104744461-A | Lactam-containing compounds and derivatives thereof as factor Xa inhibitors | BRISTOL MYERS SQUIBB CO | 2015-07-01 | — | — | CN | disclosed |