Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.65 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | TDO2 | P48775 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17560230 | 0.87 | ALDH1A1 (0.67) | TSHRIRAK4ALDH1A1HSD17B10IDO1 | |
| SCHEMBL11341203 | 0.86 | TSHR (0.59) | TSHRIRAK4ALDH1A1HSD17B10TDP1 | |
| SCHEMBL22979125 | 0.85 | TSHR (0.62) | TSHRALDH1A1HSD17B10TDP1KDM4E | |
| SCHEMBL28020067 | 0.85 | ALDH1A1 (0.72) | TSHRIRAK4ALDH1A1IDO1TDO2 | |
| SCHEMBL23332021 | 0.84 | TSHR (0.69) | TSHRIRAK4ALDH1A1HSD17B10TDP1 | |
| SCHEMBL4450648 | 0.83 | TSHR (0.56) | TSHRIRAK4ALDH1A1HSD17B10TDP1 | |
| SCHEMBL11338656 | 0.83 | TSHR (0.56) | TSHRIRAK4ALDH1A1HSD17B10TDP1 | |
| SCHEMBL9959610 | 0.83 | TSHR (0.59) | TSHRALDH1A1HSD17B10TDP1MAPK1 | |
| SCHEMBL2135648 | 0.83 | ALDH1A1 (0.59) | TSHRIRAK4ALDH1A1TDP1MAPK1 | |
| SCHEMBL28974979 | 0.82 | TSHR (0.74) | TSHRALDH1A1HSD17B10TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104829756-B | A kind of solid catalyst component for olefine polymerization and its preparation method and application | 中国科学院化学研究所 | 2018-05-15 | — | — | CN | disclosed |
| CN-104829756-A | Solid catalyst component for olefin polymerization, and preparation method and application thereof | CHINESE ACAD INST CHEMISTRY | 2015-08-12 | — | — | CN | disclosed |