SCHEMBL2135648

SCHEMBL2135648

CC(C)Oc1ccccc1C(=O)OCc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.59
IRAK4 Q9NWZ3 1/20 0.59
TDP1 Q9NUW8 3/20 0.58
L3MBTL1 Q9Y468 3/20 0.55
TSHR P16473 3/20 0.55
CYP3A4 P08684 1/20 0.55
MAPK1 P28482 1/20 0.55
HTT P42858 1/20 0.52
GPBAR1 Q8TDU6 1/20 0.52
KMT2A Q03164 3/20 0.51
SLC6A2 P23975 1/20 0.51
SLC6A3 Q01959 1/20 0.51
POLB P06746 2/20 0.50
CASP3 P42574 1/20 0.50
RAB9A P51151 1/20 0.50
SENP8 Q96LD8 1/20 0.50
SENP7 Q9BQF6 1/20 0.50
SENP6 Q9GZR1 1/20 0.50
LMNA P02545 3/20 0.47
KDM4E B2RXH2 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6285510 0.90 ALDH1A1 (0.58) ALDH1A1IRAK4TDP1L3MBTL1TSHR
SCHEMBL30531883 0.84 RORC (0.49) ALDH1A1IRAK4TDP1L3MBTL1TSHR
SCHEMBL8432905 0.83 ALDH1A1 (0.65) ALDH1A1TDP1L3MBTL1TSHRCYP3A4
SCHEMBL28020518 0.83 TSHR (0.65) ALDH1A1IRAK4TDP1TSHRCYP3A4
SCHEMBL28650754 0.83 ALDH1A1 (0.50) ALDH1A1IRAK4TDP1L3MBTL1TSHR
SCHEMBL28020067 0.81 ALDH1A1 (0.72) ALDH1A1IRAK4TDP1TSHRCYP3A4
SCHEMBL26189855 0.81 ALDH1A1 (0.68) ALDH1A1TDP1L3MBTL1TSHRCYP3A4
SCHEMBL5216859 0.81 ALDH1A1 (0.55) ALDH1A1TDP1L3MBTL1TSHRCYP3A4
SCHEMBL4064899 0.81 ALDH1A1 (0.55) ALDH1A1TDP1L3MBTL1TSHRCYP3A4
SCHEMBL5215774 0.81 ALDH1A1 (0.51) ALDH1A1TDP1L3MBTL1TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4604907-A1 A METHOD OF PROVIDING HIGH SPF TO A TOPICAL SURFACE OF A BODY Unilever IP Holdings B.V. (NL) 2025-08-27 EP disclosed
CN-119700568-A Sunscreen compositions with multiple photoprotective UV filters 科蒂公司 2025-03-28 CN disclosed
US-20240261201-A1 A METHOD OF PROVIDING HIGH SPF TO A TOPICAL SURFACE OF A BODY CONOPCO, INC., D/B/A UNILEVER (US) 2024-08-08 US disclosed
WO-2024083721-A1 A METHOD OF PROVIDING HIGH SPF TO A TOPICAL SURFACE OF A BODY UNILEVER IP HOLDINGS B.V. (NL) 2024-04-25 WO disclosed
EP-4346751-A1 A METHOD OF PROVIDING HIGH SPF TO A TOPICAL SURFACE OF A BODY Unilever IP Holdings B.V. (NL) 2024-04-10 EP disclosed
WO-2022253896-A1 A METHOD OF PROVIDING HIGH SPF TO A TOPICAL SURFACE OF A BODY UNILEVER IP HOLDINGS B.V. (NL) 2022-12-08 WO disclosed
EP-4061319-A1 SUNSCREEN COMPOSITIONS WITH MULTIPLE PHOTOPROTECTING UV FILTERS Coty Inc. (US) 2022-09-28 EP disclosed
CN-114340594-A Polyurethane gel 纳米技术有限责任公司(以生物科学博士名义) 2022-04-12 CN disclosed
WO-2021102113-A1 SUNSCREEN COMPOSITIONS WITH MULTIPLE PHOTOPROTECTING UV FILTERS COTY INC. (US) 2021-05-27 WO disclosed
EP-0676194-B2 Cosmetic or dermatological compositions comprising an alpha-hydroxy acid, salicylic acid and a retinoid BEIERSDORF AG (DE) 2015-01-07 EP disclosed
US-20120101172-A1 LIQUID OR POURABLE PROTEOSOME-FORMING BATH AND SHOWER CONCENTRATES, GALENIC APPLICATION PRODUCTS THEREOF, AND THEIR USE MERZ PHARMA GMBH & CO. KGAA (DE) 2012-04-26 US disclosed
EP-2194955-A2 SILICONE ORGANIC ELASTOMER GELS FROM ORGANOPOLYSILOXANE RESINS Dow Corning Corporation (US) 2010-06-16 EP disclosed
WO-2009042535-A2 SILICONE ORGANIC ELASTOMER GELS FROM ORGANOPOLYSILOXANE RESINS DOW CORNING CORPORATION (US) 2009-04-02 WO disclosed
EP-0676194-B1 Cosmetic or dermatological compositions comprising an alpha-hydroxy acid, salicylic acid and a retinoid BOOTS CO PLC (GB) 2001-11-14 EP disclosed
EP-0676194-A2 Cosmetic or dermatological compositions comprising an alpha-hydroxy acid, salicylic acid and a retinoid ROUSSEL UCLAF (FR) 1995-10-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240261201-A1 A METHOD OF PROVIDING HIGH SPF TO A TOPICAL SURFACE OF A BODY CUTA, ERCC4, FIBP ALDH1A1 919/4885IRAK4 4677/4885TDP1 746/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.