Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8642467 | 0.94 | LMNA (0.65) | LMNAMAPTCYP3A4MEN1KMT2A | |
| SCHEMBL934896 | 0.92 | ADRB2 (0.54) | LMNAMAPTCYP3A4MEN1KMT2A | |
| SCHEMBL20235275 | 0.88 | TSHR (0.51) | LMNAMAPTCYP3A4MEN1KMT2A | |
| SCHEMBL23971030 | 0.85 | LMNA (0.48) | LMNAMAPTCYP3A4MEN1KMT2A | |
| SCHEMBL30159042 | 0.85 | LMNA (0.48) | LMNAMAPTCYP3A4MEN1KMT2A | |
| SCHEMBL23970739 | 0.84 | LMNA (0.49) | LMNAMAPTCYP3A4MEN1KMT2A | |
| SCHEMBL28811038 | 0.84 | LMNA (0.62) | LMNAMAPTCYP3A4MEN1KMT2A | |
| SCHEMBL6462760 | 0.84 | LMNA (0.62) | LMNAMAPTCYP3A4MEN1KMT2A | |
| SCHEMBL8724910 | 0.84 | LMNA (0.67) | LMNAMAPTCYP3A4MEN1KMT2A | |
| SCHEMBL28994423 | 0.83 | TSHR (0.78) | LMNACYP3A4TSHRL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104829756-B | A kind of solid catalyst component for olefine polymerization and its preparation method and application | 中国科学院化学研究所 | 2018-05-15 | — | — | CN | disclosed |
| CN-104829756-A | Solid catalyst component for olefin polymerization, and preparation method and application thereof | CHINESE ACAD INST CHEMISTRY | 2015-08-12 | — | — | CN | disclosed |