Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.42 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15548944 | 0.82 | BCAT2 (0.61) | MKNK1MKNK2BCAT2KDM4EALDH1A1 | |
| SCHEMBL29516168 | 0.80 | TDP1 (0.52) | MKNK1MKNK2BCAT2ALDH1A1HPGD | |
| SCHEMBL1685834 | 0.80 | TDP1 (0.52) | MKNK1MKNK2BCAT2ALDH1A1HPGD | |
| SCHEMBL27947437 | 0.77 | BCAT2 (0.43) | MKNK1MKNK2AGTR1AGTR2BCAT2 | |
| SCHEMBL27909849 | 0.77 | BCAT2 (0.43) | MKNK1MKNK2AGTR1AGTR2BCAT2 | |
| SCHEMBL30108304 | 0.76 | PARP1 (0.49) | MKNK1MKNK2BCAT2ROCK2KDM4E | |
| SCHEMBL28224388 | 0.76 | PARP1 (0.49) | MKNK1MKNK2BCAT2ROCK2KDM4E | |
| SCHEMBL28700871 | 0.74 | KDM4E (0.48) | MKNK1MKNK2BCAT2KDM4EALDH1A1 | |
| SCHEMBL2330384 | 0.74 | KMT2A (0.50) | MKNK1MKNK2BCAT2KDM4EALDH1A1 | |
| SCHEMBL12592293 | 0.73 | PLA2G2A (0.50) | MKNK2ROCK2KDM4EALDH1A1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104754943-A | Active compound combinations | BAYER CROPSCIENCE AG | 2015-07-01 | — | — | CN | claimed |
| CN-104754940-A | Active compound combinations | BAYER CROPSCIENCE AG | 2015-07-01 | — | — | CN | claimed |
| CN-105658638-A | compounds with insecticidal activity | 拜耳作物科学股份公司 | 2016-06-08 | — | — | CN | disclosed |
| CN-105555136-A | Heterocyclic sulfonamido (thio) carbonyl derivatives having nematicidal properties | BAYER CROPSCIENCE AG | 2016-05-04 | — | — | CN | disclosed |
| CN-105392365-A | Heterocyclic compounds known and new as pest control agents | BAYER CROPSCIENCE AG | 2016-03-09 | — | — | CN | disclosed |
| CN-105357967-A | Method for promoting plant growth using carboxamide derivatives | BAYER CROPSCIENCE AG | 2016-02-24 | — | — | CN | disclosed |
| CN-104754943-A | Active compound combinations | BAYER CROPSCIENCE AG | 2015-07-01 | — | — | CN | disclosed |
| CN-104754940-A | Active compound combinations | BAYER CROPSCIENCE AG | 2015-07-01 | — | — | CN | disclosed |