SCHEMBL15548944

SCHEMBL15548944

NC(=O)c1cccnc1-c1ccccc1-c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 1/20 0.61
KDM4E B2RXH2 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
ADORA3 P0DMS8 1/20 0.47
CHRNB2 P17787 1/20 0.47
CHRNB4 P30926 1/20 0.47
CHRNA3 P32297 1/20 0.47
CHRNA4 P43681 1/20 0.47
MKNK1 Q9BUB5 2/20 0.46
MKNK2 Q9HBH9 2/20 0.46
PARP1 P09874 2/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
CSNK1A1 P48729 1/20 0.45
TYRO3 Q06418 1/20 0.45
DYRK1B Q9Y463 1/20 0.45
IKBKB O14920 1/20 0.44
CHUK O15111 1/20 0.44
IKBKE Q14164 1/20 0.44
PKMYT1 Q99640 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29516168 0.88 TDP1 (0.52) BCAT2TDP1MKNK1MKNK2PARP1
SCHEMBL1685834 0.88 TDP1 (0.52) BCAT2TDP1MKNK1MKNK2PARP1
SCHEMBL945856 0.86 KDM4E (0.55) BCAT2KDM4ETDP1ADORA3PARP1
SCHEMBL29916420 0.86 KDM4E (0.55) BCAT2KDM4ETDP1ADORA3PARP1
SCHEMBL27947437 0.84 BCAT2 (0.43) BCAT2KDM4ETDP1ADORA3MKNK1
SCHEMBL27909849 0.84 BCAT2 (0.43) BCAT2KDM4ETDP1ADORA3MKNK1
SCHEMBL28677174 0.83 PARP1 (0.45) BCAT2KDM4ETDP1MKNK1MKNK2
SCHEMBL28020568 0.82 MKNK1 (0.43) BCAT2KDM4EMKNK1MKNK2PARP1
SCHEMBL3820615 0.82 KDM4E (0.65) BCAT2KDM4ETDP1PARP1NPC1
SCHEMBL6616370 0.82 KDM4E (0.53) BCAT2KDM4ETDP1MKNK1MKNK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2854546-A1 COMPOSITION COMPRISING A BIOLOGICAL CONTROL AGENT AND A FUNGICIDE SELECTED FROM INHIBITORS OF THE ERGOSTEROL BIOSYNTHESIS Bayer Cropscience AG (DE) 2015-04-08 EP disclosed
WO-2013178648-A1 COMPOSITION COMPRISING A BIOLOGICAL CONTROL AGENT AND A FUNGICIDE SELECTED FROM INHIBITORS OF THE ERGOSTEROL BIOSYNTHESIS BAYER CROPSCIENCE AG (DE) 2013-12-05 WO disclosed