Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | VNN1 | O95497 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1613572 | 0.74 | GYS1 (0.50) | CCR2FEN1FAAHSIRT2SIRT1 | |
| SCHEMBL288654 | 0.74 | GYS1 (0.50) | CCR2FEN1FAAHSIRT2SIRT1 | |
| SCHEMBL7415511 | 0.73 | SIRT2 (0.50) | CCR2FEN1FAAHALDH1A1ADRA1D | |
| SCHEMBL29586287 | 0.72 | MGLL (0.55) | CCR2FEN1FAAHALDH1A1ADRA1D | |
| SCHEMBL28563919 | 0.72 | MGLL (0.55) | CCR2FEN1FAAHALDH1A1ADRA1D | |
| SCHEMBL8443442 | 0.69 | CCR2 (0.56) | CCR2FEN1FAAHALDH1A1ADRA1D | |
| SCHEMBL8872921 | 0.69 | KMT2A (0.51) | CCR2FAAH | |
| SCHEMBL25395450 | 0.69 | CCR2 (0.55) | CCR2FEN1FAAHALDH1A1ADRA1D | |
| SCHEMBL19401544 | 0.68 | GYS1 (0.54) | CCR2FAAHSIRT2SIRT1CCR3 | |
| SCHEMBL1764734 | 0.68 | GYS1 (0.54) | CCR2FAAHSIRT2SIRT1CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102482212-B | Carboxamide compounds and they are as the purposes of calpain inhibitor | ABBVIE (US) | 2015-08-26 | — | — | CN | disclosed |