SCHEMBL28021112

SCHEMBL28021112

CCN(C(=O)Cc1ccccc1)c1ccc(O)cc1

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 3/20 0.57
FNTA P49354 1/20 0.51
FNTB P49356 1/20 0.51
ALDH1A1 P00352 1/20 0.51
GLA P06280 1/20 0.51
TSHR P16473 1/20 0.51
MLYCD O95822 1/20 0.48
TRPM8 Q7Z2W7 1/20 0.48
CA2 P00918 1/20 0.47
CAMK2A Q9UQM7 1/20 0.47
LTB4R2 Q9NPC1 1/20 0.47
BCHE P06276 1/20 0.47
ACHE P22303 1/20 0.47
AKR1B1 P15121 1/20 0.46
TP53 P04637 1/20 0.45
NR1H4 Q96RI1 1/20 0.45
PDK1 Q15118 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4152623 0.94 ALDH1A1 (0.56) CNR2FNTAFNTBALDH1A1GLA
SCHEMBL4153727 0.90 ALDH1A1 (0.63) CNR2ALDH1A1GLATSHRMLYCD
SCHEMBL8012628 0.86 CNR2 (0.56) CNR2ALDH1A1GLATSHRMLYCD
SCHEMBL8016167 0.83 CNR2 (0.52) CNR2ALDH1A1GLATSHRMLYCD
SCHEMBL17602099 0.80 FNTA (0.55) FNTAFNTBALDH1A1MLYCDCA2
SCHEMBL21085193 0.80 FNTA (0.58) FNTAFNTBALDH1A1CA2CAMK2A
SCHEMBL4153701 0.78 MLYCD (0.59) ALDH1A1GLATSHRMLYCDLTB4R2
SCHEMBL5702149 0.77 ALDH1A1 (0.53) ALDH1A1GLATSHRLTB4R2TP53
SCHEMBL9295793 0.77 TP53 (0.62) CNR2ALDH1A1GLATSHRTRPM8
SCHEMBL18840276 0.75 ALDH1A1 (0.67) ALDH1A1GLATSHRMLYCDCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101180267-B Phenyl-containing n-acyl amine and aminoacid derivatives, methods for the production thereof, a pharmaceutical composition and the use thereof OBSCHESTVO S OGRANICHENNOI OTV 2015-06-17 CN disclosed