Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRK6 | P43250 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28021513 | 0.86 | GRK6 (0.66) | GRK6GAAMAPTMCL1CYP1A2 | |
| SCHEMBL8112 | 0.80 | GRK6 (1.00) | GRK6GAAMAPTMCL1CYP1A2 | |
| SCHEMBL29778809 | 0.80 | GRK6 (1.00) | GRK6GAAMAPTMCL1CYP1A2 | |
| Bromide SCHEMBL31741343 | 0.78 | GRK6 (0.96) | GRK6GAAMAPTMCL1CYP1A2 | |
| Hydrochloric Acid SCHEMBL11423019 | 0.78 | GRK6 (0.96) | GRK6GAAMAPTMCL1CYP1A2 | |
| Formaldehyde SCHEMBL27694578 | 0.75 | GRK6 (0.89) | GRK6GAAMAPTMCL1CYP1A2 | |
| Benzoquinone SCHEMBL28256504 | 0.71 | GRK6 (0.80) | GRK6GAAMAPTMCL1CYP1A2 | |
| SCHEMBL27475210 | 0.69 | GRK6 (0.75) | GRK6GAAMAPTMCL1CYP1A2 | |
| SCHEMBL27746989 | 0.69 | GRK6 (0.75) | GRK6GAAMAPTMCL1CYP1A2 | |
| Naphthoquinone SCHEMBL28258043 | 0.67 | GRK6 (0.71) | GRK6GAAMAPTMCL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109475551-A | Anti-EGFR Combinations for the Treatment of Tumors | 博笛生物科技有限公司 | 2019-03-15 | — | — | CN | disclosed |
| CN-109414497-A | Anti- HER2 for treating tumour is combined | 博笛生物科技有限公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-107074959-A | Anti- PD L1 conjugates for treating tumour | 博笛生物科技有限公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-107074958-A | Anti- PD L1 for treating tumour are combined | 博笛生物科技有限公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-106943596-A | anti-CD 20 combination for use in the treatment of tumors | 博笛生物科技（北京）有限公司 | 2017-07-14 | — | — | CN | disclosed |
| CN-106943598-A | anti-HER 2 combination for treating tumors | 博笛生物科技（北京）有限公司 | 2017-07-14 | — | — | CN | disclosed |
| CN-106535938-A | Combination therapeutic compositions and combination therapeutic methods for treating cancer | 上海博笛生物科技有限公司 | 2017-03-22 | — | — | CN | disclosed |
| CN-105899539-A | Compounds and compositions for immunotherapy | 博笛生物科技（北京）有限公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-105899537-A | Compounds and compositions targeting EGFR expressing tumors | 博笛生物科技（北京）有限公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-105899538-A | Compounds and compositions targeting HER2 positive tumors | 博笛生物科技（北京）有限公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-105440135-A | Anti-PD-L1 conjugates for the treatment of tumors | BODI BIOTECHNOLOGY CO LTD | 2016-03-30 | — | — | CN | disclosed |
| CN-105233291-A | Combination therapeutic compositions and combination therapeutic methods for treating cancer | BIRDLE BIOTECH INC | 2016-01-13 | — | — | CN | disclosed |
| CN-104861063-A | HER2 positive tumor targeting compound and composition thereof | BIRDLE BIOTECH INC | 2015-08-26 | — | — | CN | disclosed |
| CN-104861067-A | Compound for immunotherapy, and composition | BIRDLE BIOTECH INC | 2015-08-26 | — | — | CN | disclosed |
| CN-104861064-A | EGFR-expressing tumor targeting compound and composition thereof | BIRDLE BIOTECH INC | 2015-08-26 | — | — | CN | disclosed |