Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL28021244

Cc1ccc(NC(C)C)cc1.N

nearest known ligand 0.56

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 6/20 0.56
ALDH1A1 P00352 4/20 0.54
CYP3A4 P08684 2/20 0.54
THRB P10828 2/20 0.54
ALOX15 P16050 2/20 0.54
TSHR P16473 2/20 0.54
HSD17B10 Q99714 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
LMNA P02545 2/20 0.54
ALOX12 P18054 1/20 0.54
RECQL P46063 1/20 0.54
ATM Q13315 1/20 0.54
CA1 P00915 2/20 0.48
CA12 O43570 1/20 0.48
MMP8 P22894 1/20 0.48
KCNH3 Q9ULD8 1/20 0.47
MAPT P10636 2/20 0.44
RXFP1 Q9HBX9 1/20 0.44
HPGD P15428 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1454276 0.97 TDP1 (0.59) TDP1ALDH1A1CYP3A4THRBALOX15
SCHEMBL675141 0.90 TDP1 (0.68) TDP1ALDH1A1CYP3A4THRBALOX15
SCHEMBL39430 0.86 TDP1 (0.72) TDP1ALDH1A1CYP3A4THRBALOX15
SCHEMBL14586641 0.84 TEAD4 (0.48) TDP1ALDH1A1CYP3A4THRBALOX15
SCHEMBL3141077 0.81 CA1 (0.50) TDP1ALDH1A1CYP3A4THRBALOX15
SCHEMBL9934007 0.78 TDP1 (0.81) TDP1ALDH1A1CYP3A4THRBALOX15
SCHEMBL9501161 0.78 CA1 (0.52) TDP1ALDH1A1CYP3A4THRBALOX15
SCHEMBL23485010 0.77 CA1 (0.47) TDP1ALDH1A1CYP3A4THRBALOX15
SCHEMBL18559184 0.77 MAPT (0.50) TDP1ALDH1A1CYP3A4THRBALOX15
SCHEMBL1003915 0.77 CA12 (0.52) TDP1ALDH1A1CYP3A4THRBALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104649912-B Method for efficiently separating primary amine and purifying secondary amine by using microreactor 南京理工大学 2017-03-15 CN disclosed
CN-104649912-A Method for efficiently separating primary amine and purifying secondary amine by using micro reactor UNIV NANJING SCIENCE & TECH 2015-05-27 CN disclosed