Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.63 |
| ▸ | MAPT | P10636 | 9/20 | 0.63 |
| ▸ | LMNA | P02545 | 7/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | GAA | P10253 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6815260 | 0.87 | GAA (0.69) | ALDH1A1MAPTLMNASMN1; SMN2GAA | |
| SCHEMBL6811691 | 0.85 | GAA (0.71) | ALDH1A1MAPTLMNASMN1; SMN2GAA | |
| SCHEMBL29937693 | 0.83 | ALDH1A1 (0.68) | ALDH1A1MAPTLMNASMN1; SMN2GAA | |
| SCHEMBL30464734 | 0.83 | ALDH1A1 (0.66) | ALDH1A1MAPTLMNASMN1; SMN2GAA | |
| SCHEMBL29793662 | 0.83 | ALDH1A1 (0.65) | ALDH1A1MAPTLMNASMN1; SMN2GAA | |
| SCHEMBL5058298 | 0.83 | ALDH1A1 (0.71) | ALDH1A1MAPTLMNASMN1; SMN2GAA | |
| SCHEMBL4137108 | 0.83 | MAPT (0.63) | ALDH1A1MAPTLMNASMN1; SMN2GAA | |
| SCHEMBL2461666 | 0.83 | ALDH1A1 (0.66) | ALDH1A1MAPTLMNASMN1; SMN2GAA | |
| SCHEMBL2103553 | 0.83 | ALDH1A1 (0.68) | ALDH1A1MAPTLMNASMN1; SMN2GAA | |
| SCHEMBL899512 | 0.83 | ALDH1A1 (0.65) | ALDH1A1MAPTLMNASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279370-A | Compounds for targeted degradation of BRD9 | C4医药公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-104725356-A | Nitrogen heterocyclic derivatives and application thereof in medicine | GUANGDONG HEC PHARMACEUTICAL | 2015-06-24 | — | — | CN | disclosed |