Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.65 |
| ▸ | LMNA | P02545 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.59 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HTR7 | P34969 | 1/20 | 0.56 |
| ▸ | WDR5 | P61964 | 1/20 | 0.55 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.53 |
| ▸ | HTR3B | O95264 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29793662 | 1.00 | ALDH1A1 (0.65) | ALDH1A1LMNAMAPTSMN1; SMN2GAA | |
| SCHEMBL6577448 | 0.89 | HTT (0.60) | ALDH1A1LMNAMAPTSMN1; SMN2GAA | |
| Tert-Butyl Formate SCHEMBL28806303 | 0.86 | ALDH1A1 (0.55) | ALDH1A1LMNAMAPTSMN1; SMN2GAA | |
| SCHEMBL6815260 | 0.85 | GAA (0.69) | ALDH1A1LMNAMAPTSMN1; SMN2GAA | |
| SCHEMBL20876774 | 0.84 | GAA (0.72) | ALDH1A1LMNAMAPTSMN1; SMN2GAA | |
| SCHEMBL6811691 | 0.84 | GAA (0.71) | ALDH1A1LMNAMAPTSMN1; SMN2GAA | |
| SCHEMBL899660 | 0.83 | ADRB1 (0.58) | ALDH1A1LMNAGAAKMT2AMEN1 | |
| SCHEMBL4002581 | 0.83 | ADRB1 (0.58) | ALDH1A1LMNAMAPTGAAKMT2A | |
| SCHEMBL8102613 | 0.83 | ADRB1 (0.58) | ALDH1A1LMNAMAPTGAAKMT2A | |
| SCHEMBL522009 | 0.83 | ALDH1A1 (0.69) | ALDH1A1LMNAMAPTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773278-A | Quinazoline compound and application thereof in antivirus | 苏州大学 | 2022-07-22 | — | — | CN | disclosed |
| EP-2938608-B1 | SMALL MOLECULE AGONISTS OF NEUROTENSIN RECEPTOR 1 | SANFORD BURNHAM MED RES INST (US) | 2021-08-04 | — | — | EP | disclosed |
| CN-107202777-B | A kind of small molecule chip, its construction method, its application and its detection method | 广州高通生物技术有限公司 | 2019-11-26 | — | — | CN | disclosed |
| US-9868707-B2 | Small molecule agonists of neurotensin receptor 1 | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2018-01-16 | — | — | US | disclosed |
| EP-2870141-B1 | METHANETHIONE COMPOUNDS HAVING ANTIVIRAL ACTIVITY | VIRONOVA INFLUENZA AB (SE) | 2017-11-22 | — | — | EP | disclosed |
| US-9676734-B2 | Compounds and methods | VIRONOVA INFLUENZA AB (SE) | 2017-06-13 | — | — | US | disclosed |
| CN-104540810-B | Methanethione compounds having antiviral activity | 维洛诺瓦流感公司 | 2017-01-18 | — | — | CN | disclosed |
| US-20160280669-A1 | COMPOUNDS AND METHODS | VIRONOVA INFLUENZA AB (SE) | 2016-09-29 | — | — | US | disclosed |
| CN-104447625-B | Benzamide compound or its pharmaceutically acceptable salt and application thereof | 中国科学院广州生物医药与健康研究院 | 2016-08-17 | — | — | CN | disclosed |
| US-9359310-B2 | Methanethione compounds having antiviral activity | VIRONOVA INFLUENZA AB (SE) | 2016-06-07 | — | — | US | disclosed |
| US-20060149062-A1 | Sulfanyl substituted phenyl methanones | F. HOFFMANN-LA ROCHE AG (CH) | 2006-07-06 | — | — | US | disclosed |
| US-20050070539-A1 | Benzoyl-piperazine derivatives | F. HOFFMANN-LA ROCHE AG, A SWISS COMPANY (CH) | 2005-03-31 | — | — | US | disclosed |
| US-6756374-B2 | CYCLIN-DEPENDENT KINASE INHIBITORS SUCH AS (4-AMINO-2-((4-(4-METHYL-1-PIPERAZINYL)PHENYL)AMINO)-5-THIAZOLYL) (2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)METHANONE FOR TREATMENT OF BREAST, LUNG, COLON, AND PROSTATE CANCER/TUMORS | HOFFMANN-LA ROCHE INC. | 2004-06-29 | — | — | US | disclosed |
| EP-0257864-B1 | ANTIARRHYTHMIC AGENTS | Pfizer Limited (GB) | 1990-12-05 | — | — | EP | disclosed |
| US-4797401-A | 4-Substituted-1-(4-alkylsulphonamidophenyl)piperazines as antiarrhythmic agents | PFIZER INC. (US) | 1989-01-10 | — | — | US | disclosed |
| EP-0257864-A1 | Antiarrhythmic agents | Pfizer Limited (GB) | 1988-03-02 | — | — | EP | disclosed |
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060149062-A1 | Sulfanyl substituted phenyl methanones | SULT1A1, SULT2A1, SULT1E1 | ALDH1A1 871/4885LMNA 4147/4885MAPT 168/4885 |
| US-20050070539-A1 | Benzoyl-piperazine derivatives | OPRL1, ACHE, PNMT | ALDH1A1 582/4885LMNA 4692/4885MAPT 10/4885 |
| US-20160280669-A1 | COMPOUNDS AND METHODS | EIF2AK2, ZC3HAV1, HIF1AN | ALDH1A1 1319/4885LMNA 824/4885MAPT 3965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.