Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 4/20 | 0.62 |
| ▸ | POLB | P06746 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | GLA | P06280 | 3/20 | 0.60 |
| ▸ | ELANE | P08246 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | PRNP | P04156 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | RAD52 | P43351 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4157722 | 0.79 | TOP2A (0.75) | TOP2APOLBKDM4EGLAELANE | |
| SCHEMBL3668257 | 0.78 | GAA (0.50) | MAPTGAARAB9AALDH1A1LMNA | |
| SCHEMBL5852510 | 0.72 | CACNA2D1 (0.58) | POLBKDM4EGLAMAPTGAA | |
| SCHEMBL20008615 | 0.72 | MAPT (0.70) | POLBKDM4EGLAMAPTL3MBTL1 | |
| SCHEMBL27365655 | 0.72 | MEN1 (0.44) | TOP2APOLBKDM4EGLAMAPT | |
| SCHEMBL17423141 | 0.71 | TOP2A (0.59) | TOP2APOLBKDM4EGLAELANE | |
| SCHEMBL14489266 | 0.70 | POLB (0.63) | TOP2APOLBKDM4EGLAELANE | |
| SCHEMBL9524914 | 0.70 | SMN1; SMN2 (0.61) | MAPTL3MBTL1ALDH1A1LMNAATM | |
| SCHEMBL1864822 | 0.70 | POLB (0.61) | TOP2APOLBKDM4EGLAMAPT | |
| SCHEMBL14740712 | 0.69 | POLB (0.56) | TOP2APOLBKDM4EGLAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104788373-A | Method for synthesizing compound S-303 hydrochloride | UNIV WUHAN | 2015-07-22 | — | — | CN | claimed |