Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 10/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.61 |
| ▸ | GAA | P10253 | 7/20 | 0.61 |
| ▸ | RAD52 | P43351 | 5/20 | 0.61 |
| ▸ | GLA | P06280 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | MITF | O75030 | 2/20 | 0.61 |
| ▸ | TTR | P02766 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.58 |
| ▸ | TOP2A | P11388 | 4/20 | 0.54 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | GFER | P55789 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9295700 | 0.87 | POLB (0.51) | POLBKDM4EGAARAD52GLA | |
| SCHEMBL14740610 | 0.85 | POLB (0.61) | POLBKDM4EGAARAD52GLA | |
| SCHEMBL17423141 | 0.83 | TOP2A (0.59) | POLBKDM4EGAARAD52GLA | |
| SCHEMBL15867121 | 0.82 | POLB (0.63) | POLBKDM4EGAARAD52GLA | |
| SCHEMBL3360006 | 0.82 | POLB (0.67) | POLBKDM4EGAARAD52GLA | |
| SCHEMBL4157722 | 0.79 | TOP2A (0.75) | POLBKDM4EGAARAD52GLA | |
| SCHEMBL10135258 | 0.79 | SIRT5 (0.51) | POLBKDM4ERAD52LMNAALDH1A1 | |
| SCHEMBL15867118 | 0.78 | POLB (0.67) | POLBKDM4EGAARAD52GLA | |
| SCHEMBL8269610 | 0.78 | PDE10A (0.57) | KDM4E | |
| SCHEMBL7880366 | 0.78 | POLB (0.78) | POLBKDM4EGAARAD52GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026018-B | Diphenylacetylene compound | 国立大学法人大阪大学 | 2021-01-15 | — | — | CN | disclosed |
| US-20180258141-A1 | TOLAN COMPOUND | OSAKA UNIVERSITY (JP) | 2018-09-13 | — | — | US | disclosed |
| US-20160354533-A1 | ADSORBING PATHOGEN-INACTIVATING COMPOUNDS WITH POROUS PARTICLES IMMOBILIZED IN A MATRIX | CERUS CORPORATION (US) | 2016-12-08 | — | — | US | disclosed |
| US-9259525-B2 | Adsorbing pathogen-inactivating compounds with porous particles immobilized in a matrix | CERUS CORPORATION (US) | 2016-02-16 | — | — | US | disclosed |
| EP-1508345-B1 | System and method for the reduction of small organic compounds from blood products | CERUS CORP (US) | 2013-09-25 | — | — | EP | disclosed |
| EP-2493857-A1 | 9-AMINOACRIDINE DERIVATIVES, THEIR PREPARATION AND USES | Ariel-University Research and Development Company Ltd. (IL) | 2012-09-05 | — | — | EP | disclosed |
| US-20120220537-A1 | 9-AMINOACRIDINE DERIVATIVES, THEIR PREPARATION AND USES | ARIEL-UNIVERSITY RESEARCH AND DEVELOPMENT COMPANY LTD. (IL) | 2012-08-30 | — | — | US | disclosed |
| US-20120220537-A1 | 9-AMINOACRIDINE DERIVATIVES, THEIR PREPARATION AND USES | ARIEL-UNIVERSITY RESEARCH AND DEVELOPMENT COMPANY LTD. (IL) | 2012-08-30 | — | — | US | disclosed |
| US-20120220537-A1 | 9-AMINOACRIDINE DERIVATIVES, THEIR PREPARATION AND USES | ARIEL-UNIVERSITY RESEARCH AND DEVELOPMENT COMPANY LTD. (IL) | 2012-08-30 | — | — | US | disclosed |
| WO-2011051950-A1 | 9-AMINOACRIDINE DERIVATIVES, THEIR PREPARATION AND USES | ARIEL-UNIVERSITY RESEARCH AND DEVELOPMENT COMPANY LTD (IL) | 2011-05-05 | — | — | WO | disclosed |
| US-20010018179-A1 | BATCH DEVICES FOR THE REDUCTION OF COMPOUNDS FROM BIOLOGICAL COMPOSITIONS CONTAINING CELLS AND METHODS OF USE | CERUS CORPORATION | 2001-08-30 | — | — | US | disclosed |
| US-20010009756-A1 | FLOW DEVICES FOR THE REDUCTION OF COMPOUNDS FROM BIOLOGICAL COMPOSITIONS AND METHODS OF USE | CERUS CORPORATION | 2001-07-26 | — | — | US | disclosed |
| CN-1284896-A | Flow device for the reduction of compounds from biological compositions and methods of use | CERUS CORP (US) | 2001-02-21 | — | — | CN | disclosed |
| CN-1284897-A | Batch devices for reduction of compounds from biological compositions containing cells and methods of use | CERUS CORP (US) | 2001-02-21 | — | — | CN | disclosed |
| EP-1051249-A1 | FLOW DEVICES FOR THE REDUCTION OF COMPOUNDS FROM BIOLOGICAL COMPOSITIONS AND METHODS OF USE | Cerus Corporation (US) | 2000-11-15 | — | — | EP | disclosed |
| EP-1044066-A1 | BATCH DEVICES FOR THE REDUCTION OF COMPOUNDS FROM BIOLOGICAL COMPOSITIONS CONTAINING CELLS AND METHODS OF USE | Cerus Corporation (US) | 2000-10-18 | — | — | EP | disclosed |
| EP-0954374-A1 | METHODS AND DEVICES FOR THE REDUCTION OF SMALL ORGANIC COMPOUNDS FROM BLOOD PRODUCTS | Cerus Corporation (US) | 1999-11-10 | — | — | EP | disclosed |
| WO-1999034914-A1 | BATCH DEVICES FOR THE REDUCTION OF COMPOUNDS FROM BIOLOGICAL COMPOSITIONS CONTAINING CELLS AND METHODS OF USE | CERUS CORPORATION (US) | 1999-07-15 | — | — | WO | disclosed |
| WO-1999034915-A1 | FLOW DEVICES FOR THE REDUCTION OF COMPOUNDS FROM BIOLOGICAL COMPOSITIONS AND METHODS OF USE | CERUS CORPORATION (US) | 1999-07-15 | — | — | WO | disclosed |
| WO-1998030327-A1 | METHODS AND DEVICES FOR THE REDUCTION OF SMALL ORGANIC COMPOUNDS FROM BLOOD PRODUCTS | CERUS CORPORATION (US) | 1998-07-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120220537-A1 | 9-AMINOACRIDINE DERIVATIVES, THEIR PREPARATION AND USES | MPG, PRMT9, AADAT | POLB 842/4885KDM4E 502/4885GAA 2176/4885 |
| US-20180258141-A1 | TOLAN COMPOUND | TAP1, GRN, TSG101 | POLB 578/4885KDM4E 4844/4885GAA 1001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.