SCHEMBL28021962

SCHEMBL28021962

FC(F)(c1ccccc1)c1ccccc1.[Ti]

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.61
ALDH1A1 P00352 2/20 0.61
PTPN1 P18031 2/20 0.46
KCNN4 O15554 3/20 0.45
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA5A P35218 1/20 0.44
CA9 Q16790 1/20 0.44
KIF11 P52732 1/20 0.43
LTA4H P09960 1/20 0.40
MAPK1 P28482 1/20 0.39
PGK1 P00558 1/20 0.37
PGK2 P07205 1/20 0.37
CYP1A2 P05177 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36
ALOX15 P16050 1/20 0.36
CES1 P23141 1/20 0.36
RORC P51449 1/20 0.36
TRPV6 Q9H1D0 1/20 0.36
PTPN5 P54829 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1108511 0.97 TSHR (0.65) TSHRALDH1A1PTPN1KCNN4CA1
SCHEMBL507958 0.81 TSHR (0.48) TSHRALDH1A1CA1CA2CA5A
SCHEMBL693451 0.81 TSHR (0.48) TSHRALDH1A1PTPN1KCNN4CA1
SCHEMBL7938599 0.81 TSHR (0.48) TSHRALDH1A1KIF11MAPK1CYP1A2
SCHEMBL624627 0.81 ALDH1A1 (0.48) TSHRALDH1A1PTPN1KCNN4CA1
SCHEMBL3626453 0.81 TSHR (0.48) TSHRALDH1A1PTPN1KCNN4CA1
SCHEMBL26294659 0.81 ALDH1A1 (0.55) TSHRALDH1A1PTPN1CA1CA2
SCHEMBL1538909 0.76 TSHR (0.65) TSHRALDH1A1PTPN1KCNN4CA1
SCHEMBL9723026 0.76 ALDH1A1 (0.65) TSHRALDH1A1PTPN1KCNN4CA1
Trifluoromethylbenzene SCHEMBL8692 0.76 TSHR (1.00) TSHRALDH1A1PTPN1KCNN4CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104854150-B Activator compositions, their preparation, and their use in catalysts 阿尔比马尔公司 2017-05-24 CN disclosed
CN-104854150-A Activator compositions, their preparation, and their use in catalysts ALBEMARLE CORP 2015-08-19 CN disclosed