Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | EIF4A1 | P60842 | 6/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15535530 | 0.92 | FAAH (0.41) | FAAHCES1EIF4A1CYP19A1CYP11B1 | |
| SCHEMBL1197845 | 0.76 | TSHR (0.60) | KCNH2KCNJ1TSHRALDH1A1 | |
| SCHEMBL545799 | 0.75 | ABL1 (0.53) | CYP19A1CYP11B1CYP11B2TSHRNPC1 | |
| SCHEMBL826630 | 0.74 | TSHR (0.50) | CES1TSHRNPC1ALDH1A1LMNA | |
| SCHEMBL3133571 | 0.71 | APP (0.51) | TSHRNPC1ALDH1A1LMNAMAPT | |
| SCHEMBL447386 | 0.71 | TSHR (0.58) | KCNH2KCNJ1TSHRALDH1A1 | |
| SCHEMBL14133969 | 0.70 | TRPV1 (0.45) | CYP11B1CYP11B2TSHRNPC1ALDH1A1 | |
| SCHEMBL546042 | 0.69 | ABL1 (0.44) | FAAHCES1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL28022472 | 0.69 | ASPH (0.37) | FAAHEIF4A1CYP11B1CYP11B2NPC1 | |
| SCHEMBL23365096 | 0.68 | NPC1 (0.42) | FAAHCES1TSHRNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104781234-A | Carboline and carbazole based imaging agents for detecting neurological dysfunction | LILLY CO ELI | 2015-07-15 | — | — | CN | disclosed |