Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.38 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.30 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.30 |
| ▸ | ODC1 | P11926 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9471992 | 0.79 | LDHA (0.42) | LDHASRR | |
| SCHEMBL27328829 | 0.72 | MAPT (0.38) | LDHASRR | |
| SCHEMBL28906293 | 0.71 | AKR1B1 (0.41) | OR51E2 | |
| SCHEMBL28822456 | 0.70 | ODC1 (0.33) | ODC1 | |
| SCHEMBL4882584 | 0.70 | AKR1B1 (0.39) | OR51E2 | |
| SCHEMBL994719 | 0.69 | LDHA (0.42) | LDHASRR | |
| SCHEMBL1059262 | 0.67 | LDHA (0.47) | LDHASRR | |
| SCHEMBL4882056 | 0.67 | LDHA (0.40) | LDHASRR | |
| SCHEMBL14973493 | 0.65 | LDHA (0.44) | LDHASRR | |
| SCHEMBL7544594 | 0.65 | LDHA (0.44) | LDHASRR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113652407-A | Carbonyl reductase mutant and application thereof in asymmetric synthesis of bi-chiral compound | 浙江工业大学 | 2021-11-16 | — | — | CN | disclosed |
| CN-110214136-A | Pyrazole derivatives as MALT1 inhibitor | 詹森药业有限公司 | 2019-09-06 | — | — | CN | disclosed |
| CN-106459003-B | Pyrazole amide derivatives | 帝人制药株式会社 | 2019-06-21 | — | — | CN | disclosed |
| CN-109689631-A | Method for preparing 3- (trifluoromethyl) pyrazine-2-formic ether | 隆萨有限公司 | 2019-04-26 | — | — | CN | disclosed |
| CN-109071545-A | New Pyrazolopyrimidine derivative | 拜耳动物保健有限责任公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-107922377-A | Hepatitis B virus assembly effector | 美国印第安纳大学研究和技术公司 | 2018-04-17 | — | — | CN | disclosed |
| CN-105283184-B | For treating the pyrazolo pyridine derivatives of carcinoma of urinary bladder | 赛诺菲 | 2018-01-26 | — | — | CN | disclosed |
| CN-104470903-B | Heterocyclic compounds and methods of their use | 诺华股份有限公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-106459003-A | Pyrazole amide derivatives | 帝人制药株式会社 | 2017-02-22 | — | — | CN | disclosed |
| CN-105848483-A | Quinolinyl modulators of roryt | 詹森药业有限公司 | 2016-08-10 | — | — | CN | disclosed |
| CN-105828823-A | Hepatitis B virus assembly effectors | 美国印第安纳大学研究和技术公司 | 2016-08-03 | — | — | CN | disclosed |
| CN-104768932-A | Heteroaryl inhibitors of PDE4 | TETRA DISCOVERY PARTNERS LLC | 2015-07-08 | — | — | CN | disclosed |
| CN-102476984-A | Preparation method of 1,1, 1-trifluoroacetone | SINOCHEM LANTIAN CO LTD | 2012-05-30 | — | — | CN | disclosed |