Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 12/20 | 0.43 |
| ▸ | MMP1 | P03956 | 8/20 | 0.43 |
| ▸ | MMP13 | P45452 | 8/20 | 0.43 |
| ▸ | MMP9 | P14780 | 8/20 | 0.43 |
| ▸ | MMP3 | P08254 | 7/20 | 0.43 |
| ▸ | MMP7 | P09237 | 6/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27950308 | 0.85 | PSIP1 (0.44) | MMP1MMP13MMP7 | |
| SCHEMBL27755158 | 0.78 | F2 (0.38) | MMP2MMP1MMP13MMP9MMP3 | |
| SCHEMBL27887475 | 0.78 | F2 (0.38) | MMP2MMP1MMP13MMP9MMP3 | |
| SCHEMBL28762515 | 0.76 | MEN1 (0.47) | MMP1MMP13MMP7SLC1A3SLC1A2 | |
| SCHEMBL27538492 | 0.73 | KMT2A (0.42) | EGFRERBB2 | |
| SCHEMBL23768103 | 0.71 | CA2 (0.47) | MMP2MMP1MMP13MMP9MMP3 | |
| SCHEMBL19881153 | 0.70 | CA2 (0.50) | MMP2MMP1MMP13MMP9MMP3 | |
| SCHEMBL342966 | 0.70 | GSK3B (0.48) | FPR2CA1CA2 | |
| SCHEMBL8481401 | 0.70 | NHERF1 (0.47) | MMP2MMP1MMP13MMP9CA12 | |
| SCHEMBL28022931 | 0.70 | PLCG1 (0.42) | MMP2MMP1MMP13MMP9MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105102449-A | Antiviral compounds | HOFFMANN LA ROCHE | 2015-11-25 | — | — | CN | disclosed |