Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.42 |
| ▸ | FEN1 | P39748 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17394409 | 0.78 | POLB (0.49) | MEN1KMT2AGAAPOLB | |
| SCHEMBL28159883 | 0.78 | KMT2A (0.54) | MEN1KMT2AGAAPOLBALDH1A1 | |
| SCHEMBL30150274 | 0.76 | KMT2A (0.79) | MEN1KMT2AGAAPOLBALDH1A1 | |
| SCHEMBL24512314 | 0.71 | CNR2 (0.47) | MEN1KMT2AGAAPOLBALDH1A1 | |
| SCHEMBL30899306 | 0.71 | CNR2 (0.47) | MEN1KMT2AGAAPOLBALDH1A1 | |
| SCHEMBL24512138 | 0.71 | CNR2 (0.48) | MEN1KMT2AGAAPOLBALDH1A1 | |
| SCHEMBL28160428 | 0.71 | KMT2A (0.61) | MEN1KMT2AGAAALDH1A1CNR2 | |
| SCHEMBL978033 | 0.69 | ALOX5AP (0.59) | MEN1KMT2AGAAPOLBALOX5AP | |
| SCHEMBL3450810 | 0.69 | LMNA (0.54) | MEN1KMT2AALDH1A1ALOX5APFEN1 | |
| SCHEMBL24129913 | 0.69 | ACHE (0.45) | GAAPOLBL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105102449-A | Antiviral compounds | HOFFMANN LA ROCHE | 2015-11-25 | — | — | CN | disclosed |