Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.52 |
| ▸ | ACLY | P53396 | 2/20 | 0.49 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.41 |
| ▸ | FEN1 | P39748 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4127355 | 0.85 | KAT6A (0.44) | PTGS2ACLYKAT6AALOX5APFEN1 | |
| SCHEMBL937206 | 0.82 | PTGS2 (0.61) | PTGS2ACLYPTGS1RAB9AKMT2A | |
| SCHEMBL29415408 | 0.82 | PTGS2 (0.61) | PTGS2ACLYPTGS1RAB9AKMT2A | |
| SCHEMBL31287755 | 0.81 | PTGS1 (0.47) | PTGS2KAT6AALOX5APFEN1PTGS1 | |
| SCHEMBL4801781 | 0.81 | KAT6A (0.46) | PTGS2ACLYKAT6A | |
| Hydrochloric Acid SCHEMBL7352630 | 0.80 | PTGS2 (0.59) | PTGS2ACLYPTGS1RAB9AKMT2A | |
| SCHEMBL8770199 | 0.79 | PTGS2 (0.53) | PTGS2ACLYPTGS1RAB9AKMT2A | |
| SCHEMBL8658514 | 0.79 | PTGS2 (0.62) | PTGS2ACLYALOX5APFEN1PTGS1 | |
| SCHEMBL4198455 | 0.79 | PTGS2 (0.62) | PTGS2ACLYALOX5APFEN1PTGS1 | |
| SCHEMBL9538025 | 0.78 | PTGS2 (0.52) | PTGS2ACLYALOX5APFEN1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105102449-A | Antiviral compounds | HOFFMANN LA ROCHE | 2015-11-25 | — | — | CN | claimed |