Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 2/20 | 0.46 |
| ▸ | ACLY | P53396 | 4/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | CHAT | P28329 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 2/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | HNF4A | P41235 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4127355 | 0.85 | KAT6A (0.44) | KAT6AACLYPTGS2CASP1HNF4A | |
| SCHEMBL232659 | 0.82 | CASP1 (0.47) | PTGS2TSHRSMN1; SMN2CASP1CHAT | |
| SCHEMBL29743050 | 0.82 | CASP1 (0.47) | PTGS2TSHRSMN1; SMN2CASP1CHAT | |
| SCHEMBL31287755 | 0.81 | PTGS1 (0.47) | KAT6APTGS2 | |
| SCHEMBL28022697 | 0.81 | PTGS2 (0.52) | KAT6AACLYPTGS2 | |
| SCHEMBL392931 | 0.81 | TSHR (0.41) | PTGS2TSHRSMN1; SMN2CASP1CHAT | |
| SCHEMBL30166530 | 0.81 | TSHR (0.41) | PTGS2TSHRSMN1; SMN2CASP1CHAT | |
| Lithium SCHEMBL3173875 | 0.80 | CASP1 (0.46) | PTGS2TSHRSMN1; SMN2CASP1CHAT | |
| SCHEMBL29194067 | 0.80 | CASP1 (0.46) | PTGS2TSHRSMN1; SMN2CASP1CHAT | |
| SCHEMBL28934633 | 0.80 | CASP1 (0.46) | PTGS2TSHRSMN1; SMN2CASP1CHAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924554-A1 | SULPHONAMIDE DERIVATIVES | Biotie Therapies Corp. (FI) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007034035-A1 | SULPHONAMIDE DERIVATIVES | BIOTIE THERAPIES CORPORATION (FI) | 2007-03-29 | — | — | WO | disclosed |