Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | GHSR | Q92847 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4107931 | 0.86 | MAPT (0.50) | POLBKMT2AALDH1A1EPHX2MAPT | |
| SCHEMBL28022376 | 0.85 | CA2 (0.42) | POLBGHSRCA12CA1CA2 | |
| SCHEMBL2634144 | 0.82 | SPR (0.44) | POLBGHSRCA12CA1CA2 | |
| SCHEMBL23245656 | 0.82 | MAPT (0.46) | POLBKMT2AALDH1A1EPHX2MAPT | |
| SCHEMBL21412280 | 0.82 | MAPT (0.46) | POLBKMT2AALDH1A1EPHX2MAPT | |
| SCHEMBL14916026 | 0.81 | FPR2 (0.48) | NAMPTCHRNA7 | |
| SCHEMBL28159864 | 0.81 | POLB (0.50) | POLBF10MEN1KMT2AALDH1A1 | |
| SCHEMBL21412278 | 0.80 | AKR1C3 (0.41) | GHSRNAMPTKMT2AMAPTGAA | |
| SCHEMBL23245846 | 0.80 | AKR1C3 (0.41) | GHSRNAMPTKMT2AMAPTGAA | |
| SCHEMBL25286183 | 0.80 | HPGD (0.54) | POLBMEN1KMT2AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105102449-B | Antiviral compound | 豪夫迈·罗氏有限公司 | 2017-06-13 | — | — | CN | disclosed |
| CN-105102449-A | Antiviral compounds | HOFFMANN LA ROCHE | 2015-11-25 | — | — | CN | disclosed |