SCHEMBL28022985

SCHEMBL28022985

O=S(=O)(O)c1cc(Cl)c(O)c(Cl)c1.[NaH]

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ING2 Q9H160 1/20 0.50
HSD17B10 Q99714 4/20 0.46
TSHR P16473 3/20 0.46
TTR P02766 2/20 0.46
ALDH1A1 P00352 2/20 0.46
CYP3A4 P08684 1/20 0.46
RECQL P46063 1/20 0.46
MEP1B Q16820 2/20 0.44
THRB P10828 1/20 0.42
LCK P06239 1/20 0.41
FYN P06241 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
CYP2C19 P33261 1/20 0.41
HIF1A Q16665 1/20 0.41
LMNA P02545 1/20 0.41
CA1 P00915 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3857115 0.98 ING2 (0.52) ING2HSD17B10TSHRTTRALDH1A1
SCHEMBL6935562 0.85 CASP6 (0.53) ING2HSD17B10TSHRALDH1A1CYP3A4
SCHEMBL21931019 0.83 CA1 (0.44) ING2TSHRTTRALDH1A1CYP3A4
SCHEMBL8459698 0.80 HSD17B10 (0.50) HSD17B10TSHRTTRALDH1A1CYP3A4
SCHEMBL3139602 0.80 CA1 (0.45) ING2HSD17B10TSHRALDH1A1CYP3A4
SCHEMBL1347471 0.80 HSD17B10 (0.50) HSD17B10TSHRTTRALDH1A1CYP3A4
SCHEMBL1056064 0.78 HSD17B10 (0.48) HSD17B10TSHRTTRALDH1A1CYP3A4
SCHEMBL29534252 0.77 HSD17B10 (0.48) ING2HSD17B10TSHRALDH1A1CYP3A4
SCHEMBL31149846 0.77 HSD17B10 (0.48) ING2HSD17B10TSHRALDH1A1CYP3A4
SCHEMBL7824972 0.77 NSD2 (0.68) ALDH1A1CA1CA2NSD2CASP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104677959-A Reagent, kit and test paper for determining concentration of oxalic acid, and preparation method for test paper WUHAN COMFORT BIO TECH CO LTD 2015-06-03 CN disclosed