Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.68 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.68 |
| ▸ | CASP6 | P55212 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 6/20 | 0.54 |
| ▸ | CA2 | P00918 | 6/20 | 0.54 |
| ▸ | CA9 | Q16790 | 6/20 | 0.54 |
| ▸ | CA12 | O43570 | 5/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10628283 | 0.87 | CASP6 (0.79) | NSD2GAAPLCG1DNMT1CASP6 | |
| SCHEMBL30741200 | 0.84 | NSD2 (0.56) | NSD2GAAPLCG1DNMT1CASP6 | |
| SCHEMBL9297794 | 0.84 | NSD2 (0.56) | NSD2GAAPLCG1DNMT1CASP6 | |
| SCHEMBL5369611 | 0.82 | NSD2 (0.61) | NSD2GAAPLCG1DNMT1CASP6 | |
| SCHEMBL2810591 | 0.81 | NSD2 (0.53) | NSD2GAAPLCG1DNMT1CASP6 | |
| SCHEMBL177115 | 0.81 | CASP6 (1.00) | NSD2GAAPLCG1DNMT1CASP6 | |
| SCHEMBL10477276 | 0.80 | NSD2 (0.59) | NSD2GAAPLCG1DNMT1CASP6 | |
| Hydrochloric Acid SCHEMBL7754103 | 0.80 | NSD2 (0.59) | NSD2GAAPLCG1DNMT1CASP6 | |
| Potassium Ion SCHEMBL10477278 | 0.80 | NSD2 (0.59) | NSD2GAAPLCG1DNMT1CASP6 | |
| SCHEMBL22556884 | 0.80 | KIF18A (0.54) | NSD2GAAPLCG1DNMT1CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
| US-4245110-A | Polyalkylene oxide-containing urethane polyols with sulphonic acid groups | BAYER AKTIENGESELLSCHAFT (DE) | 1981-01-13 | — | — | US | disclosed |