SCHEMBL8459698

SCHEMBL8459698

O=S(=O)(c1cc(Cl)c(O)c(Cl)c1)c1cc(Cl)c(O)c(Cl)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 4/20 0.50
TSHR P16473 3/20 0.50
TTR P02766 2/20 0.50
ALDH1A1 P00352 2/20 0.50
CYP3A4 P08684 2/20 0.50
RECQL P46063 1/20 0.50
MEP1B Q16820 2/20 0.47
THRB P10828 1/20 0.46
CYP1A2 P05177 1/20 0.44
CYP2C9 P11712 1/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44
CYP2C19 P33261 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
HIF1A Q16665 1/20 0.44
CA1 P00915 3/20 0.43
CA2 P00918 3/20 0.43
MAPK1 P28482 2/20 0.40
HPGD P15428 2/20 0.40
CA9 Q16790 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1347471 1.00 HSD17B10 (0.50) HSD17B10TSHRTTRALDH1A1CYP3A4
SCHEMBL2811005 0.86 GAA (0.50) HSD17B10TSHRALDH1A1CYP3A4RECQL
SCHEMBL3857115 0.82 ING2 (0.52) HSD17B10TSHRTTRALDH1A1CYP3A4
SCHEMBL1056064 0.82 HSD17B10 (0.48) HSD17B10TSHRTTRALDH1A1CYP3A4
SCHEMBL1128272 0.80 HSD17B10 (0.46) HSD17B10TSHRTTRALDH1A1CYP3A4
SCHEMBL28022985 0.80 ING2 (0.50) HSD17B10TSHRTTRALDH1A1CYP3A4
SCHEMBL5564627 0.80 CA1 (0.64) HSD17B10TSHRTTRALDH1A1CYP3A4
SCHEMBL9655024 0.80 HSD17B10 (0.46) HSD17B10TSHRTTRALDH1A1CYP3A4
SCHEMBL11366209 0.78 DUSP5 (0.55) HSD17B10TSHRTTRALDH1A1CYP3A4
SCHEMBL13286834 0.78 MEP1B (0.56) HSD17B10TSHRTTRALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0739879-B1 Halogen-containing cyanate ester, process for producing the same and thermosetting resin composition containing the same SUMITOMO CHEMICAL CO (JP) 1999-12-22 EP disclosed
EP-0739879-A1 Halogen-containing cyanate ester, process for producing the same and thermosetting resin composition containing the same SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-10-30 EP disclosed
EP-0346761-B1 Process for the preparation of aromatic polycarbonates BAYER AG (DE) 1994-12-21 EP disclosed