Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL814047 | 0.84 | TSHR (0.36) | TSHRALDH1A1THRB | |
| SCHEMBL5574536 | 0.84 | TSHR (0.36) | TSHRALDH1A1THRB | |
| SCHEMBL28418180 | 0.77 | TSHR (0.38) | TRPA1TRPV1TSHRALDH1A1 | |
| SCHEMBL29241694 | 0.74 | TSHR (0.36) | TSHRALDH1A1THRB | |
| SCHEMBL10597576 | 0.72 | ALDH1A1 (0.33) | TSHRALDH1A1 | |
| SCHEMBL4612822 | 0.71 | ALDH1A1 (0.36) | TSHRALDH1A1THRB | |
| SCHEMBL20183974 | 0.70 | TSHR (0.53) | TSHRALDH1A1THRB | |
| SCHEMBL26525 | 0.70 | TSHR (0.42) | TSHRALDH1A1THRB | |
| SCHEMBL20183942 | 0.69 | TSHR (0.56) | TRPA1TRPV1TSHRALDH1A1THRB | |
| SCHEMBL5360818 | 0.69 | TSHR (0.40) | TSHRALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104874031-A | Polyurethane derivative for simulating human fibrinolytic system and vascular endothelial system, preparation method and preparation method of related product | UNIV SOOCHOW | 2015-09-02 | — | — | CN | claimed |
| CN-104874031-B | Polyurethane derivative for simulating human fibrinolytic system and vascular endothelial system, preparation method and preparation method of related product | 苏州大学 | 2017-10-10 | — | — | CN | disclosed |
| CN-104874031-A | Polyurethane derivative for simulating human fibrinolytic system and vascular endothelial system, preparation method and preparation method of related product | UNIV SOOCHOW | 2015-09-02 | — | — | CN | disclosed |
| CN-101942105-B | Polyurethane material capable of dissolving plasma clot in high efficiency and preparation thereof | UNIV SOOCHOW | 2012-06-27 | — | — | CN | disclosed |
| CN-101942105-A | Polyurethane material capable of dissolving plasma clot in high efficiency and preparation thereof | UNIV SUZHOU | 2011-01-12 | — | — | CN | disclosed |