SCHEMBL5574536

SCHEMBL5574536

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nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.36
ALDH1A1 P00352 1/20 0.34
THRB P10828 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL814047 1.00 TSHR (0.36) TSHRALDH1A1THRB
SCHEMBL4612822 0.86 ALDH1A1 (0.36) TSHRALDH1A1THRB
SCHEMBL28023153 0.84 TRPA1 (0.35) TSHRALDH1A1THRB
SCHEMBL5360818 0.83 TSHR (0.40) TSHRALDH1A1THRB
SCHEMBL516924 0.83 TSHR (0.34) TSHRALDH1A1
SCHEMBL1850276 0.83 TSHR (0.34) TSHRALDH1A1
SCHEMBL5177573 0.83 TSHR (0.50) TSHRALDH1A1THRB
SCHEMBL5360012 0.82 TSHR (0.42) TSHR
SCHEMBL9613843 0.81 TSHR (0.41) TSHRALDH1A1
SCHEMBL5355947 0.81 TSHR (0.45) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1866357-A1 (METH)ACRYLOYL GROUP-CONTAINING AROMATIC ISOCYANATE COMPOUND AND PRODUCTION PROCESS THEREOF Showa Denko K.K. (JP) 2007-12-19 EP disclosed
WO-2006103979-A1 (METH)ACRYLOYL GROUP-CONTAINING AROMATIC ISOCYANATE COMPOUND AND PRODUCTION PROCESS THEREOF SHOWA DENKO K.K. (JP) 2006-10-05 WO disclosed