Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | NPC1 | O15118 | 5/20 | 0.64 |
| ▸ | RAB9A | P51151 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | MAPK10 | P53779 | 6/20 | 0.60 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.57 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.56 |
| ▸ | MGAM | O43451 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953857 | 0.84 | KDM4E (0.66) | KDM4EKMT2ANPC1RAB9AMAPT | |
| SCHEMBL3977907 | 0.84 | KDM4E (0.66) | KDM4EKMT2ANPC1RAB9AMAPT | |
| SCHEMBL28465286 | 0.78 | KMT2A (1.00) | KDM4EKMT2ANPC1RAB9AMAPT | |
| SCHEMBL5798716 | 0.76 | KDM4E (0.55) | KDM4EKMT2ANPC1RAB9AMAPT | |
| SCHEMBL16403339 | 0.76 | PLAUR (0.61) | KDM4EKMT2ANPC1RAB9AMAPT | |
| SCHEMBL28449520 | 0.75 | KDM4E (0.64) | KDM4EKMT2ANPC1RAB9AMAPT | |
| SCHEMBL6936350 | 0.73 | RAB9A (0.78) | KDM4EKMT2ANPC1RAB9AMAPT | |
| SCHEMBL7105109 | 0.73 | RAB9A (0.78) | KDM4EKMT2ANPC1RAB9AMAPT | |
| SCHEMBL1568280 | 0.73 | ALDH1A1 (0.59) | KDM4EKMT2ANPC1RAB9AMAPT | |
| SCHEMBL1898286 | 0.72 | NPC1 (0.63) | KDM4EKMT2ANPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104892573-A | 3-vinyl-quinoxaline-2(1H)-one derivatives acting on FGFR-1, preparation method and uses thereof | UNIV WENZHOU MEDICAL | 2015-09-09 | — | — | CN | claimed |
| CN-104892573-A | 3-vinyl-quinoxaline-2(1H)-one derivatives acting on FGFR-1, preparation method and uses thereof | UNIV WENZHOU MEDICAL | 2015-09-09 | — | — | CN | disclosed |
| CN-104892573-A | 3-vinyl-quinoxaline-2(1H)-one derivatives acting on FGFR-1, preparation method and uses thereof | UNIV WENZHOU MEDICAL | 2015-09-09 | — | — | CN | disclosed |
| CN-104892573-A | 3-vinyl-quinoxaline-2(1H)-one derivatives acting on FGFR-1, preparation method and uses thereof | UNIV WENZHOU MEDICAL | 2015-09-09 | — | — | CN | disclosed |